Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL11829479 | 1.00 | TSHR (0.70) | — | |
| Ethylenediamine SCHEMBL29214721 | 0.89 | TSHR (0.89) | — | |
| Monoethanolamine SCHEMBL2273335 | 0.89 | — | — | |
| Ethylenediamine SCHEMBL1234596 | 0.89 | — | — | |
| Monoethanolamine SCHEMBL15808596 | 0.89 | TSHR (0.89) | — | |
| Monoethanolamine SCHEMBL1331364 | 0.82 | — | — | |
| Monoethanolamine SCHEMBL29663853 | 0.82 | — | — | |
| Monoethanolamine SCHEMBL1332111 | 0.82 | — | — | |
| Monoethanolamine SCHEMBL14675689 | 0.82 | TSHR (1.00) | — | |
| Monoethanolamine SCHEMBL1644 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107073678-B | Polishing layer imporosity formed body, polishing pad and polishing method | 株式会社可乐丽 | 2019-11-19 | — | — | CN | disclosed |
| CN-110225933-A | Aqueous polyurethane resin combination | 株式会社艾迪科 | 2019-09-10 | — | — | CN | disclosed |
| EP-2688953-B1 | PHOSPHOROUS-CONTAINING FLAME RETARDANTS FOR POLYURETHANE FOAMS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-05-01 | — | — | EP | disclosed |
| CN-108409960-A | A method of preserving materials synthesis polyurethane using carbon dioxide | 内蒙古工业大学 | 2018-08-17 | — | — | CN | disclosed |
| CN-107429561-A | Handle the fracturing fluid and method of hydrocarbon containing formation | 通用电气(GE)贝克休斯有限责任公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-107073678-A | Non-porous molded body for polishing layer, polishing pad, and polishing method | 株式会社可乐丽 | 2017-08-18 | — | — | CN | disclosed |
| CN-107001818-A | Black pigments comprising graphenic carbon particles | PPG工业俄亥俄公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-104387559-B | Acoustical absorption heat preserving spraying combined polyether of half perforate and preparation method thereof | 山东诺威新材料有限公司 | 2017-06-09 | — | — | CN | disclosed |
| CN-106660805-A | Graphenic carbon particle co-dispersions and methods of making same | PPG工业俄亥俄公司 | 2017-05-10 | — | — | CN | disclosed |
| EP-1457836-B2 | Developing solution for lithographic printing plate precursor and method for preparing lithographic printing plate | FUJIFILM CORP (JP) | 2016-08-17 | — | — | EP | disclosed |
| EP-1457837-A2 | Developing solution for heat-sensitive lithographic printing plate precursor and method for peparing lithographic printing plate | FUJI PHOTO FILM CO., LTD. (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-20040063036-A1 | Method of making lithographic printing plate | FUJI PHOTO FILM CO., LTD. | 2004-04-01 | — | — | US | disclosed |
| EP-1400856-A2 | Method of making lithographic printing plate | FUJI PHOTO FILM CO., LTD. (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-20040053168-A1 | Exposing the heat-sensitive plate to light, and developing with an alkaline solution comprising sulfactants and salts; improve image contrast, resist to scratch, dispersing the development sludge | FUJI PHOTO FILM CO., LTD. | 2004-03-18 | — | — | US | disclosed |
| EP-1398151-A2 | Method of making lithographic printing plate | Fuji Photo Film Co., Ltd. (JP) | 2004-03-17 | — | — | EP | disclosed |
| CN-1074746-C | Prepn. process of hydrazine hydrate | MITSUBISHI GAS CHEMICAL CO (JP) | 2001-11-14 | — | — | CN | disclosed |
| CN-1148027-A | Prepn. process of hydrazine hydrate | MITSUBISHI GAS CHEMICAL CO (JP) | 1997-04-23 | — | — | CN | disclosed |
| EP-0671460-A1 | ELECTROVISCOUS FLUID | Tonen Corporation (JP) | 1995-09-13 | — | — | EP | disclosed |
| US-4847184-A | SCANNING, CARBONIZATION OF SUBSTRATE SURFACES | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1989-07-11 | — | — | US | disclosed |
| US-4066578-A | CONDENSATION POLYMERIZATION, CROSSLINKING | W. R. GRACE & CO. (US) | 1978-01-03 | — | — | US | disclosed |