Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8646509 | 0.90 | MAPT (0.51) | MAPTTDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL12548607 | 0.89 | KMT2A (0.52) | MAPTTDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL2743140 | 0.88 | KMT2A (0.49) | MAPTTDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL13779477 | 0.88 | MAPT (0.49) | MAPTTDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL12187356 | 0.87 | MAPT (0.44) | MAPTTDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL3607757 | 0.87 | MAPT (0.44) | MAPTTDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL12761349 | 0.86 | ESR1 (0.54) | MAPTTDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL13266308 | 0.84 | MAPT (0.48) | MAPTTDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL12134166 | 0.83 | MAPT (0.40) | MAPTTDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL21387331 | 0.83 | MAPT (0.41) | MAPTTDP1L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2889688-B1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, AND IMIDE COMPOUND | CANON KK (JP) | 2017-09-13 | — | — | EP | disclosed |
| US-20110305981-A1 | IMAGING MEMBERS HAVING IMPROVED IMAGING LAYERS | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2011-12-15 | — | — | US | disclosed |
| US-7553594-B2 | Electrophotographic photosensitive member, method of manufacturing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | disclosed |
| US-20080199794-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2008-08-21 | — | — | US | disclosed |
| US-20080199795-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2008-08-21 | — | — | US | disclosed |
| US-20070003850-A1 | Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus | FUJI XEROX CO., LTD. (JP) | 2007-01-04 | — | — | US | disclosed |