SCHEMBL3607757

SCHEMBL3607757

CCC(C)(CC)Oc1ccc(C(C)(C)c2ccc(OC(=O)c3ccccc3)c(C)c2)cc1C

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
KMT2A Q03164 4/20 0.43
MEN1 O00255 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43
NPSR1 Q6W5P4 1/20 0.41
MRGPRX4 Q96LA9 1/20 0.40
VDR P11473 1/20 0.40
CYP3A4 P08684 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
SLC6A3 Q01959 1/20 0.38
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12134166 0.93 MAPT (0.40) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL12187356 0.90 MAPT (0.44) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL12045003 0.87 MAPT (0.48) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL14040042 0.86 CYP1A2 (0.41) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL15241746 0.86 MAPT (0.42) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL13662195 0.86 RXRA (0.42) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL8646509 0.86 MAPT (0.51) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL12548607 0.84 KMT2A (0.52) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL14817425 0.84 MAPT (0.43) MAPTTDP1L3MBTL1KMT2AMEN1
SCHEMBL12352730 0.84 VDR (0.36) NPSR1VDRESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1983375-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MATERIAL, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC DEVICDE CANON KK (JP) 2017-09-27 EP disclosed
EP-1734410-B1 ELECTROPHOTOGRAPHY PHOTOSENSITIVE BODY, METHOD FOR PRODUCING ELECTROPHOTOGRAPHY PHOTOSENSITIVE BODY, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPH CANON KK (JP) 2016-05-11 EP disclosed
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8343699-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2013-01-01 US disclosed
US-8211602-B2 Image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-03 US disclosed
US-20120099898-A1 ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2012-04-26 US disclosed
US-20120039630-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2012-02-16 US disclosed
US-20110104597-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2011-05-05 US disclosed
EP-2317390-A1 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus Canon Kabushiki Kaisha (JP) 2011-05-04 EP disclosed
US-20100316412-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2010-12-16 US disclosed
US-7704657-B2 Electrophotographic photosensitive member, method of manufacturing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2010-04-27 US disclosed
US-7622238-B2 Process for producing electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2009-11-24 US disclosed
EP-2109006-A1 PROCESS FOR MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR Canon Kabushiki Kaisha (JP) 2009-10-14 EP disclosed
US-20090180800-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-07-16 US disclosed
US-7534534-B2 Electrophotographic Photosensitive member, method for manufacturing electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2009-05-19 US disclosed
US-20090053634-A1 Image Forming Apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2009-02-26 US disclosed
EP-1983375-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MATERIAL, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC DEVICDE Canon Kabushiki Kaisha (JP) 2008-10-22 EP disclosed
EP-1983373-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS Canon Kabushiki Kaisha (JP) 2008-10-22 EP disclosed
US-20080220356-A1 Electrophotographic photoreceptor, process cartridge and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2008-09-11 US disclosed
US-20080124637-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2008-05-29 US disclosed