SCHEMBL12047271

SCHEMBL12047271

CCCCCCCCCCCCCCCCCCOC(=O)OC1CC(C)(C)N(OCC(C)(C)O)C(C)(C)C1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.33
RAD52 P43351 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
EPHX2 P34913 4/20 0.32
EPHX1 P07099 1/20 0.32
GBA2 Q9HCG7 1/20 0.32
ACHE P22303 6/20 0.31
TSHR P16473 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13714967 0.89 NAAA (0.32) NAAARAD52NPSR1EPHX2EPHX1
SCHEMBL12047222 0.85 NAAA (0.35) NAAAEPHX2EPHX1GBA2ACHE
SCHEMBL6298154 0.83 NAAA (0.48) NAAA
SCHEMBL9926866 0.83 NAAA (0.48) NAAA
SCHEMBL6298143 0.83 NAAA (0.48) NAAA
SCHEMBL4867060 0.83 NAAA (0.48) NAAA
SCHEMBL39244 0.83 NAAA (0.48) NAAA
SCHEMBL15299845 0.83 NAAA (0.48) NAAA
SCHEMBL17085426 0.83 NAAA (0.48) NAAA
SCHEMBL45485 0.83 NAAA (0.48) NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9133121-B2 Weakly basic hindered amines compounds having carbonate skeletons, synthetic resin compositions and coating compositions NEGISHI YOSHINORI (JP) 2015-09-15 US disclosed
US-8785527-B2 Synthetic resin composition and automotive interior/exterior material comprising the same ADEKA CORPORATION (JP) 2014-07-22 US disclosed
US-20130023611-A1 Weakly Basic Hindered Amines Compounds Having Carbonate Skeletons, Synthetic Resin Compositions And Coating Compositions ADEKA CORPORATION (JP) 2013-01-24 US disclosed
US-8329787-B2 Weakly basic hindered amines compounds having carbonate skeletons, synthetic resin compositions and coating compositions ADEKA CORPORATION (JP) 2012-12-11 US disclosed
US-20110319537-A1 VINYL CHLORIDE RESIN COMPOSITION ADEKA CORPORATION (JP) 2011-12-29 US disclosed
US-20110028611-A1 SYNTHETIC RESIN COMPOSITION AND AUTOMOTIVE INTERIOR/EXTERIOR MATERIAL COMPRISING THE SAME ADEKA CORPORATION (JP) 2011-02-03 US disclosed
US-20100190898-A1 Weakly Basic Hindered Amines Compounds Having Carbonate Skeletons, Synthetic Resin Compositions And Coating Compositions NEGISHI YOSHINORI 2010-07-29 US disclosed
US-20090111699-A1 Weakly Basic Hindered Amines Having Carbonate Skeletons, Synthetic Resin Compositions, And Coating Compositions ADEKA CORPORATION (JP) 2009-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130023611-A1 Weakly Basic Hindered Amines Compounds Having Carbonate Skeletons, Synthetic Resin Compositions And Coating Compositions H1-2, H1-4, H1-3 NAAA 217/4885RAD52 932/4885NPSR1 141/4885
US-20090111699-A1 Weakly Basic Hindered Amines Having Carbonate Skeletons, Synthetic Resin Compositions, And Coating Compositions H1-2, H1-3, H1-4 NAAA 164/4885RAD52 783/4885NPSR1 156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.