SCHEMBL12061298

SCHEMBL12061298

CC1OC(COC2(C(=O)O)CC(O)C(C)C([C@H](O)[C@H](O)CO)O2)C(O)C(O)C1C

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CD22 P20273 16/20 0.44
▸ MAG P20916 2/20 0.42
▸ SIGLEC7 Q9Y286 2/20 0.41
▸ SELL P14151 1/20 0.40
▸ SELP P16109 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18718049 0.94 CD22 (0.46) CD22MAGSELLSELP
SCHEMBL21334206 0.91 CD22 (0.47) CD22MAGSIGLEC7SELLSELP
SCHEMBL18718069 0.91 CD22 (0.47) CD22MAGSIGLEC7SELLSELP
SCHEMBL18718058 0.91 CD22 (0.47) CD22MAGSIGLEC7SELLSELP
SCHEMBL16407968 0.89 CD22 (0.48) CD22MAG
SCHEMBL15215708 0.89 CD22 (0.48) CD22MAG
SCHEMBL17853991 0.88 CD22 (0.48) CD22MAGSIGLEC7
SCHEMBL25787323 0.87 CD22 (0.51) CD22MAG
SCHEMBL12061293 0.87 MAG (0.52) CD22MAGSIGLEC7SELLSELP
SCHEMBL17857272 0.86 MAG (0.46) CD22MAGSIGLEC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150064240-A1 MUC1 Based Glycolipopeptide Vaccine with Adjuvant ONCOTHYREON INC. 2015-03-05 — — US disclosed
US-8889616-B2 MUC1 based glycolipopeptide vaccine with adjuvant ONCOTHYREON INC. (US) 2014-11-18 — — US disclosed
US-8329639-B2 MUC1 based glycolipopeptide vaccine with adjuvant ONCOTHYREON INC. (US) 2012-12-11 — — US disclosed
US-20120282329-A1 MUC1 Based Glycolipopeptide Vaccine with Adjuvant ONCOTHYREON INC. (US) 2012-11-08 — — US disclosed
US-20120219617-A1 MUC1 Based Glycolipopeptide Vaccine with Adjuvant ONCOTHYREON INC. (US) 2012-08-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120282329-A1 MUC1 Based Glycolipopeptide Vaccine with Adjuvant MUC1, LGALS3BP, ST3GAL3 CD22 320/4885MAG 99/4885SIGLEC7 4/4885
US-20150064240-A1 MUC1 Based Glycolipopeptide Vaccine with Adjuvant MUC1, LGALS3BP, ST3GAL3 CD22 320/4885MAG 99/4885SIGLEC7 4/4885
US-20120219617-A1 MUC1 Based Glycolipopeptide Vaccine with Adjuvant MUC1, LGALS3BP, ST3GAL3 CD22 320/4885MAG 99/4885SIGLEC7 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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