Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4894125 | 0.85 | PDE4A (0.35) | PDE4A | |
| SCHEMBL4895779 | 0.81 | EPHX1 (0.36) | PDE4A | |
| SCHEMBL5475632 | 0.78 | — | — | |
| SCHEMBL18801013 | 0.72 | — | — | |
| SCHEMBL27969171 | 0.68 | PDE4A (0.34) | PDE4A | |
| SCHEMBL1341781 | 0.65 | ALDH1A1 (0.33) | — | |
| SCHEMBL11158159 | 0.65 | ALDH1A1 (0.33) | — | |
| SCHEMBL5039648 | 0.65 | ALDH1A1 (0.33) | — | |
| SCHEMBL26618853 | 0.63 | PDE4A (0.30) | PDE4A | |
| SCHEMBL14908 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147038-A1 | HETEROCYCLYL-PYRIDINYL-BASED BIPHOSPHONIC ACID, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, COMPOSITION THEREOF AND METHOD OF USE THEREOF | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2011-12-01 | — | — | WO | disclosed |