Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CSNK1A1L | Q8N752 | 1/20 | 0.36 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14774054 | 0.89 | LMNA (0.34) | BRD4SMN1; SMN2MLKL | |
| SCHEMBL12065619 | 0.82 | IDO1 (0.38) | BRD4MLKL | |
| SCHEMBL14770563 | 0.82 | BRD4 (0.41) | BRD4PTGS2PTGS1SCDTDO2 | |
| SCHEMBL12065255 | 0.80 | SCN10A (0.40) | MLKL | |
| SCHEMBL14763413 | 0.80 | BCHE (0.37) | MLKL | |
| SCHEMBL12066566 | 0.79 | PRCP (0.42) | SMN1; SMN2MLKL | |
| SCHEMBL14762718 | 0.79 | PDE2A (0.36) | MLKL | |
| Oxalic Acid SCHEMBL14762710 | 0.78 | PDE2A (0.38) | MLKL | |
| Phosphoric Acid SCHEMBL14763404 | 0.78 | PDE2A (0.38) | — | |
| SCHEMBL12065252 | 0.77 | CACNA1C (0.42) | BRD4ALDH1A1MLKL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011148956-A1 | FUSED IMIDAZOLE DERIVATIVE | トーアエイヨー株式会社 (JP) | 2011-12-01 | — | — | WO | disclosed |