Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.51 |
| ▸ | GLS | O94925 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 7/20 | 0.47 |
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4719541 | 0.92 | KDM4E (0.48) | ACKR3GLSMEN1ALDH1A1MAPT | |
| SCHEMBL18768306 | 0.86 | ACKR3 (0.53) | ACKR3GLSMEN1ALDH1A1MAPT | |
| SCHEMBL2025339 | 0.85 | ACKR3 (0.53) | ACKR3GLSMEN1ALDH1A1MAPT | |
| SCHEMBL2025336 | 0.85 | ACKR3 (0.53) | ACKR3GLSMEN1ALDH1A1MAPT | |
| SCHEMBL19934828 | 0.84 | ACKR3 (0.47) | ACKR3GLSMEN1ALDH1A1MAPT | |
| SCHEMBL13181804 | 0.84 | ACKR3 (0.53) | ACKR3GLSMEN1ALDH1A1MAPT | |
| SCHEMBL3023628 | 0.83 | KDM4E (0.56) | GLSALDH1A1KDM1AHPGDEPHX1 | |
| SCHEMBL24862784 | 0.83 | ACKR3 (0.48) | ACKR3GLSMEN1ALDH1A1MAPT | |
| SCHEMBL18767210 | 0.83 | ACKR3 (0.50) | ACKR3GLSMEN1ALDH1A1MAPT | |
| SCHEMBL4014855 | 0.83 | ACKR3 (0.60) | ACKR3GLSMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011148962-A1 | NOVEL HETEROCYCLIC COMPOUND OR SALT THEREOF | 大正製薬株式会社 (JP) | 2011-12-01 | — | — | WO | disclosed |