Icosapent

Icosapent

SCHEMBL120666

CC/C=C/C/C=C/C/C=C/C/C=C/C/C=C/CCCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 1.00
PPARG P37231 8/20 1.00
F7 P08709 7/20 1.00
F3 P13726 7/20 1.00
CYP19A1 P11511 6/20 1.00
PPARD Q03181 6/20 1.00
PPARA Q07869 6/20 1.00
PTGS1 P23219 5/20 1.00
OXER1 Q8TDS5 4/20 1.00
KMT2A Q03164 3/20 1.00
RXRA P19793 2/20 1.00
ADORA3 P0DMS8 1/20 1.00
FFAR1 O14842 5/20 0.85
MAPT P10636 4/20 0.85
L3MBTL1 Q9Y468 3/20 0.85
KDM4E B2RXH2 3/20 0.85
LMNA P02545 3/20 0.85
CYP3A4 P08684 3/20 0.85
HPGD P15428 3/20 0.85
ALOX15 P16050 3/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Icosapent SCHEMBL18185487 1.00 ALDH1A1 (1.00) ALDH1A1PPARGF7F3CYP19A1
Icosapent SCHEMBL1648318 1.00 ALDH1A1 (1.00) ALDH1A1PPARGF7F3CYP19A1
SCHEMBL12828369 1.00 ALDH1A1 (1.00) ALDH1A1PPARGF7F3CYP19A1
Icosapent SCHEMBL1648015 1.00 ALDH1A1 (1.00) ALDH1A1PPARGF7F3CYP19A1
Icosapent SCHEMBL2877007 1.00 ALDH1A1 (1.00) ALDH1A1PPARGF7F3CYP19A1
Icosapent SCHEMBL2877002 1.00 ALDH1A1 (1.00) ALDH1A1PPARGF7F3CYP19A1
SCHEMBL23417014 1.00 ALDH1A1 (1.00) ALDH1A1PPARGF7F3CYP19A1
Icosapent SCHEMBL18185494 1.00 ALDH1A1 (1.00) ALDH1A1PPARGF7F3CYP19A1
Icosapent SCHEMBL18274961 1.00 ALDH1A1 (1.00) ALDH1A1PPARGF7F3CYP19A1
Icosapent SCHEMBL18185412 1.00 ALDH1A1 (1.00) ALDH1A1PPARGF7F3CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3033 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4642830-A1 (METH)ACRYLATED ISOCYANURATE MIXTURE, PROCESS FOR PREPARING SAME, AND USES THEREOF ARKEMA France (FR) 2025-11-05 EP claimed
WO-2024141286-A1 (METH)ACRYLATED ISOCYANURATE MIXTURE, PROCESS FOR PREPARING SAME, AND USES THEREOF ARKEMA FRANCE (FR) 2024-07-04 WO claimed
CN-117665134-A Biomarker combination for Alzheimer disease or mild cognitive impairment and application thereof 深圳市绘云生物科技有限公司 2024-03-08 CN claimed
CN-117571864-A Method for detecting fatty acid content 中国计量科学研究院 2024-02-20 CN claimed
EP-4294375-A1 METHODS OF LOADING EXTRACELLULAR VESICLES Lonza Sales AG (CH) 2023-12-27 EP claimed
CN-117177739-A Method for loading extracellular vesicles 隆萨销售股份有限公司 2023-12-05 CN claimed
CN-117054550-A Method for detecting 38 fatty acids in erythrocyte membrane 福建医科大学 2023-11-14 CN claimed
CN-116858976-A Method for detecting total fatty acid content of 11 fatty acids in blood by high performance liquid chromatography-tandem mass spectrometry and application 北京和合医学诊断技术股份有限公司 2023-10-10 CN claimed
CN-116626089-A Method for judging yellow-feather broiler chicken feeding components based on flavor analysis 中国农业科学院农产品加工研究所 2023-08-22 CN claimed
CN-116462821-A Thermoplastic polyurethane elastomer material, preparation method and application thereof 万华化学集团股份有限公司 2023-07-21 CN claimed
EP-0161422-B1 ALKANOLAMINE DERIVATIVES AND PLATELET AGGREGATION INHIBITORS CONTAINING THE SAME AS AN ACTIVE INGREDIENT TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) 1989-03-01 EP claimed
CN-88101370-A Pharmaceutical composition acting on cardiovascular system and preparation method thereof 1988-11-09 CN claimed
EP-0244832-A2 Preparations containing insaturated fatty acids for the synthesis of prostaglandins and of fatty hydroxy acids in biological systems HOECHST AKTIENGESELLSCHAFT (DE) 1987-11-11 EP claimed
US-4704393-A ANTITUMOR AGENTS TERUMO KABUSHIKI KAISHA (JP) 1987-11-03 US claimed
EP-0162924-A1 5-FLUOROURACIL DERIVATIVES AND MEDICINAL PREPARATION CONTAINING SAME TERUMO KABUSHIKI KAISHA (JP) 1985-12-04 EP claimed
US-4526902-A Combined fatty acid composition for treatment or prophylaxis of thrombo-embolic conditions CENTURY LABORATORIES, INC. (US) 1985-07-02 US claimed
US-4223011-A OXYALKYLENE, AMINOALKYLENE; POLYACRYLIC ACID FERRUTI PAOLO 1980-09-16 US claimed
US-4211865-A STARCH OR DEXTRAN ESTERIFIED WITH EICOSATRIEN-, EICOSATETRAEN-, OR EICOSAPENTAENOIC ACID FERRUTI PAOLO (IT) 1980-07-08 US claimed
US-4145320-A BOUND TO POLY-ACRYLIC OR METHACRYLIC UNITS THROUGH OXYALKYLENIC, AMINOALKYLENIC, OR OXYAMINOALKYLENIC CHAINS FERRUTI PAOLO 1979-03-20 US claimed
US-4097602-A CIS-8,11,14-EICOSATRIENOIC ACID OR ESTER THOMAS JEFFERSON UNIVERSITY 1978-06-27 US claimed