Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14351215 | 0.80 | LMNA (0.46) | LMNATRPA1PTGS1CACNA1CBCHE | |
| SCHEMBL10843605 | 0.76 | LMNA (0.63) | LMNATRPA1PTGS1CACNA1CBCHE | |
| SCHEMBL10843609 | 0.73 | LMNA (0.48) | LMNATRPA1PTGS1CACNA1CBCHE | |
| SCHEMBL15878674 | 0.73 | LMNA (0.53) | LMNATRPA1PTGS1CACNA1CBCHE | |
| SCHEMBL1101926 | 0.72 | TYR (0.50) | LMNATRPA1PTGS1CACNA1CBCHE | |
| SCHEMBL28250769 | 0.71 | LMNA (0.47) | LMNATRPA1PTGS1CACNA1CBCHE | |
| SCHEMBL17229430 | 0.71 | LMNA (0.47) | LMNATRPA1PTGS1CACNA1CBCHE | |
| SCHEMBL9618308 | 0.71 | PTGS1 (0.46) | LMNATRPA1PTGS1CACNA1CBCHE | |
| SCHEMBL9660963 | 0.71 | LMNA (0.43) | LMNATRPA1PTGS1CACNA1CBCHE | |
| SCHEMBL17229433 | 0.70 | LMNA (0.50) | LMNATRPA1PTGS1CACNA1CBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147819-A2 | SOLID-STATE PROCESSING OF PI-CONJUGATED MATERIALS | Eidgenössische Technische Hochschule Zürich (CH) | 2011-12-01 | — | — | WO | disclosed |