Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1317503 | 0.85 | PDPK1 (0.61) | TSHRGAAHSD17B10RAB9APDPK1 | |
| SCHEMBL3124312 | 0.83 | CCNC (0.46) | TSHRGAAHSD17B10 | |
| SCHEMBL14804589 | 0.82 | PDPK1 (0.61) | TSHRGAAHSD17B10RAB9APDPK1 | |
| SCHEMBL1319357 | 0.82 | PDPK1 (0.61) | TSHRGAAHSD17B10RAB9APDPK1 | |
| SCHEMBL1317217 | 0.80 | PDPK1 (0.48) | TSHRGAAHSD17B10RAB9APDPK1 | |
| SCHEMBL1317221 | 0.80 | PDPK1 (0.48) | TSHRGAAHSD17B10RAB9APDPK1 | |
| SCHEMBL1317219 | 0.80 | PDPK1 (0.48) | TSHRGAAHSD17B10RAB9APDPK1 | |
| SCHEMBL1319776 | 0.79 | PDPK1 (0.47) | TSHRGAAHSD17B10RAB9APDPK1 | |
| SCHEMBL1319773 | 0.79 | PDPK1 (0.47) | TSHRGAAHSD17B10RAB9APDPK1 | |
| SCHEMBL1319780 | 0.79 | PDPK1 (0.47) | TSHRGAAHSD17B10RAB9APDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011149874-A2 | N-PHENYL IMIDAZOLE CARBOXAMIDE INHIBITORS OF 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE-1 | SCHERING CORPORATION (US) | 2011-12-01 | — | — | WO | disclosed |