Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CHKA | P35790 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | ME2 | P23368 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17368563 | 1.00 | CA12 (0.47) | CA12CA2CA9AKR1C3MAPK1 | |
| SCHEMBL19648915 | 0.91 | CA2 (0.44) | CA12CA2CA9AKR1C3MAPK1 | |
| SCHEMBL13285321 | 0.89 | CA12 (0.56) | CA12CA2CA9AKR1C3MAPK1 | |
| SCHEMBL12069706 | 0.87 | MAPT (0.41) | CA12CA2CA9AKR1C3MAPK1 | |
| SCHEMBL12069757 | 0.87 | BRD4 (0.42) | CA12CA2CA9AKR1C3MAPK1 | |
| SCHEMBL5153946 | 0.87 | CA12 (0.54) | CA12CA2CA9AKR1C3MAPK1 | |
| SCHEMBL18409048 | 0.86 | AKR1C3 (0.57) | CA12CA2CA9AKR1C3MAPK1 | |
| SCHEMBL12069726 | 0.86 | AKR1C3 (0.57) | CA12CA2CA9AKR1C3MAPK1 | |
| SCHEMBL19844473 | 0.85 | DPP4 (0.39) | CA12CA2CA9AKR1C3MAPK1 | |
| SCHEMBL19844466 | 0.85 | AKR1C3 (0.44) | CA12CA2CA9AKR1C3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2580289-B1 | BLACK DICHROIC DYE | BASF SE (DE) | 2017-11-29 | — | — | EP | disclosed |
| US-9057020-B2 | Black dichroic dye | BASF SE (DE) | 2015-06-16 | — | — | US | disclosed |
| US-20130092874-A1 | BLACK DICHROIC DYE | BASF SE (DE) | 2013-04-18 | — | — | US | disclosed |
| WO-2011157614-A1 | BLACK DICHROIC DYE | BASF SE (DE) | 2011-12-22 | — | — | WO | disclosed |