Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12068358 | 0.90 | HSD11B1 (0.84) | HSD11B1 | |
| SCHEMBL12069449 | 0.89 | HSD11B1 (0.79) | HSD11B1 | |
| SCHEMBL12068592 | 0.88 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL14680851 | 0.87 | HSD11B1 (0.77) | HSD11B1 | |
| SCHEMBL12070117 | 0.86 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL12068593 | 0.86 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL12070111 | 0.84 | HSD11B1 (0.77) | HSD11B1 | |
| SCHEMBL16666275 | 0.83 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL12068324 | 0.83 | HSD11B1 (0.84) | HSD11B1 | |
| SCHEMBL12070543 | 0.81 | HSD11B1 (0.84) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011149213-A2 | NOVEL DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST 11Β-HSD1, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | 주식회사 이큐스앤자루 (KR) | 2011-12-01 | — | — | WO | disclosed |