Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.76 |
| ▸ | NEK2 | P51955 | 1/20 | 0.76 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.76 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.76 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | INSR | P06213 | 3/20 | 0.46 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.45 |
| ▸ | EP300 | Q09472 | 3/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.44 |
| ▸ | SENP3 | Q9H4L4 | 3/20 | 0.43 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12070546 | 1.00 | CHEK1 (0.76) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL29921971 | 0.87 | CHEK1 (1.00) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL4078292 | 0.87 | CHEK1 (1.00) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL8653147 | 0.83 | TDP1 (0.80) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL3694623 | 0.82 | MEN1 (0.73) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL5044740 | 0.82 | MEN1 (0.64) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL5044742 | 0.82 | MEN1 (0.64) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL22299738 | 0.81 | CHEK1 (0.61) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL17804072 | 0.79 | KMT2A (0.54) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL14866951 | 0.79 | KMT2A (0.64) | CHEK1NEK2LIMK1DYRK1ACLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011157614-A1 | BLACK DICHROIC DYE | BASF SE (DE) | 2011-12-22 | — | — | WO | disclosed |