Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 1.00 |
| ▸ | NEK2 | P51955 | 1/20 | 1.00 |
| ▸ | LIMK1 | P53667 | 1/20 | 1.00 |
| ▸ | DYRK1A | Q13627 | 1/20 | 1.00 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 1.00 |
| ▸ | EP300 | Q09472 | 3/20 | 0.55 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.55 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4078292 | 1.00 | CHEK1 (1.00) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL2886998 | 0.88 | CHEK1 (0.79) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL31689542 | 0.88 | CHEK1 (0.79) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL29922382 | 0.88 | CHEK1 (0.79) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL12070545 | 0.87 | CHEK1 (0.76) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL12070546 | 0.87 | CHEK1 (0.76) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL29919884 | 0.85 | CHEK1 (0.73) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL8990307 | 0.85 | CHEK1 (0.73) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL8720110 | 0.80 | CHEK1 (0.65) | CHEK1NEK2LIMK1DYRK1ACLK4 | |
| SCHEMBL27613656 | 0.79 | CA2 (0.64) | CHEK1NEK2LIMK1DYRK1ACLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11447507-B2 | Sulfur scavenging materials | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2022-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11447507-B2 | Sulfur scavenging materials | TST, MPST, MGMT | CHEK1 2794/4885NEK2 3588/4885LIMK1 4006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.