Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.51 |
| ▸ | TTK | P33981 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 12/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 10/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14060824 | 0.84 | PIK3CG (0.44) | TTKPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL12506777 | 0.83 | TTK (0.60) | CYP17A1TTKPIK3CGPIK3CDPIK3CA | |
| SCHEMBL12507038 | 0.82 | PIK3CG (0.51) | CYP17A1TTKPIK3CGPIK3CDPIK3CA | |
| SCHEMBL13636152 | 0.80 | KDR (0.47) | CYP17A1TTKPIK3CGPIK3CDPIK3CA | |
| SCHEMBL12068441 | 0.77 | TTK (0.49) | TTK | |
| SCHEMBL13636141 | 0.75 | KDR (0.52) | TTKAAK1ABL1KDR | |
| SCHEMBL1932107 | 0.74 | PIK3CG (0.47) | TTKPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL13636158 | 0.74 | KDR (0.41) | TTKPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL12909576 | 0.73 | PIK3CG (0.50) | PIK3CGPIK3CDPIK3CAPIK3CBDYRK1A | |
| SCHEMBL1933358 | 0.73 | PIK3CG (0.46) | PIK3CGPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9555022-B2 | Substituted triazolopyridines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-01-31 | — | — | US | disclosed |
| US-20130156756-A1 | Substituted Triazolopyridines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-06-20 | — | — | US | disclosed |
| WO-2012160029-A1 | SUBSTITUTED TRIAZOLOPYRIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2012-11-29 | — | — | WO | disclosed |
| WO-2011157688-A1 | SUBSTITUTED TRIAZOLOPYRIDINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2011-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130156756-A1 | Substituted Triazolopyridines | CCND2, CCND1, QDPR | CYP17A1 3514/4885TTK 791/4885PIK3CG 1972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.