Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11885689 | 0.90 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL9985567 | 0.90 | HSD11B1 (0.83) | HSD11B1 | |
| SCHEMBL9985682 | 0.89 | HSD11B1 (0.82) | HSD11B1 | |
| SCHEMBL11029913 | 0.89 | HSD11B1 (0.82) | HSD11B1 | |
| SCHEMBL9986309 | 0.89 | HSD11B1 (0.81) | HSD11B1 | |
| SCHEMBL9985138 | 0.87 | HSD11B1 (0.78) | HSD11B1 | |
| SCHEMBL9985416 | 0.87 | HSD11B1 (0.78) | HSD11B1 | |
| SCHEMBL9985414 | 0.86 | HSD11B1 (0.77) | HSD11B1 | |
| SCHEMBL9986697 | 0.86 | HSD11B1 (0.77) | HSD11B1 | |
| SCHEMBL9986101 | 0.84 | HSD11B1 (0.74) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161128-A1 | AZASPIROHEXANONES AS INHIBITORS OF 11-BETA-HSD1 FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-12-29 | — | — | WO | disclosed |