Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14450799 | 0.86 | MCHR1 (0.49) | ADRB1MCHR1RORCCYP2D6HRH1 | |
| SCHEMBL14924424 | 0.86 | MCHR1 (0.49) | ADRB1MCHR1RORCCYP2D6HRH1 | |
| SCHEMBL27389111 | 0.86 | MCHR1 (0.49) | ADRB1MCHR1RORCCYP2D6HRH1 | |
| SCHEMBL8726331 | 0.79 | ADRB1 (0.50) | ADRB1MCHR1HTR2AHTR2CGPR119 | |
| SCHEMBL24123779 | 0.74 | ADRB1 (0.44) | ADRB1MCHR1NPC1USP2ALDH1A1 | |
| SCHEMBL23636672 | 0.74 | CYP3A4 (0.50) | HTR2AHTR2CALDH1A1 | |
| SCHEMBL8723815 | 0.73 | ADRB1 (0.44) | ADRB1MCHR1HTR2AHTR2CGPR119 | |
| SCHEMBL7604480 | 0.73 | MCHR1 (0.54) | MCHR1KCNH2 | |
| SCHEMBL25016051 | 0.73 | ADRB1 (0.47) | ADRB1GPR119DPP4ALDH1A1LMNA | |
| SCHEMBL25016623 | 0.73 | ADRB1 (0.47) | ADRB1GPR119DPP4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011162515-A2 | NOVEL FUSED PYRIMIDINE DERIVATIVES FOR INHD3ITION OF TYROSINE KINASE ACTIVITY | HANMI HOLDINGS CO. , LTD. (KR) | 2011-12-29 | — | — | WO | disclosed |