Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.57 |
| ▸ | CALML3 | P27482 | 6/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | SDHA | P31040 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1394379 | 0.89 | MAOA (0.56) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1394167 | 0.87 | MAOA (0.62) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL3087382 | 0.87 | MAOA (0.57) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1394145 | 0.87 | MAOA (0.57) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1393700 | 0.86 | MAOA (0.57) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1394065 | 0.86 | MAOA (0.55) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1394066 | 0.86 | CALML3 (0.62) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1393520 | 0.85 | MAOA (0.56) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1393807 | 0.85 | MAOA (0.57) | MAOACALML3MAOBLMNAPTGS1 | |
| SCHEMBL1393295 | 0.85 | MAOA (0.60) | MAOACALML3MAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2492264-A2 | Biaryl Heterocyclic Compounds And Methods Of Making And Using The Same | Rib-X Pharmaceuticals, Inc. (US) | 2012-08-29 | — | — | EP | disclosed |