Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.49 |
| ▸ | CALML3 | P27482 | 4/20 | 0.45 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | SDHA | P31040 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1394312 | 0.95 | MAOA (0.51) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL1394032 | 0.94 | MAOA (0.50) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL1393970 | 0.93 | MAOA (0.49) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL1394346 | 0.93 | MAOA (0.49) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL1394363 | 0.93 | MAOA (0.49) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL1393441 | 0.92 | MAOA (0.48) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL1394342 | 0.91 | MAOA (0.50) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL1393435 | 0.91 | MAOA (0.52) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL1394253 | 0.91 | MAOA (0.49) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL1393099 | 0.90 | MAOA (0.54) | MAOACALML3MAOBPTGS1SDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2492264-A2 | Biaryl Heterocyclic Compounds And Methods Of Making And Using The Same | Rib-X Pharmaceuticals, Inc. (US) | 2012-08-29 | — | — | EP | disclosed |