Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.55 |
| ▸ | CALML3 | P27482 | 6/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | SDHA | P31040 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1394041 | 1.00 | MAOA (0.55) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL13528675 | 1.00 | MAOA (0.55) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL10259730 | 0.94 | MAOA (0.55) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL1394314 | 0.94 | MAOA (0.55) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL3093905 | 0.92 | MAOA (0.56) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL1393183 | 0.87 | MAOA (0.53) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL3183809 | 0.87 | MAOA (0.60) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL3183805 | 0.87 | MAOA (0.60) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL6023183 | 0.87 | MAOA (0.56) | MAOACALML3MAOBPTGS1SDHA | |
| SCHEMBL3179763 | 0.87 | MAOA (0.56) | MAOACALML3MAOBPTGS1SDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2492264-A2 | Biaryl Heterocyclic Compounds And Methods Of Making And Using The Same | Rib-X Pharmaceuticals, Inc. (US) | 2012-08-29 | — | — | EP | disclosed |