Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.49 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10017294 | 0.89 | CYP2A6 (0.48) | CYP2A6ALDH1A1CYP3A4CYP1A2NISCH | |
| SCHEMBL7163648 | 0.77 | NISCH (0.39) | ALDH1A1NISCHKDM4EMAPTHPGD | |
| SCHEMBL5171062 | 0.75 | CYP2A6 (0.61) | CYP2A6ALDH1A1CYP3A4CYP1A2NISCH | |
| SCHEMBL31038279 | 0.75 | NISCH (0.36) | NISCHKDM4EMAPT | |
| SCHEMBL30269982 | 0.73 | HTR2A (0.49) | CYP2A6ALDH1A1CYP3A4CYP1A2NISCH | |
| SCHEMBL4790022 | 0.73 | HTR2A (0.49) | CYP2A6ALDH1A1CYP3A4CYP1A2NISCH | |
| SCHEMBL16272068 | 0.72 | ALDH1A1 (0.45) | CYP2A6ALDH1A1CYP3A4CYP1A2NISCH | |
| SCHEMBL30473120 | 0.71 | CYP2A6 (1.00) | CYP2A6ALDH1A1CYP3A4CYP1A2CYP2E1 | |
| SCHEMBL29419014 | 0.71 | CYP2A6 (1.00) | CYP2A6ALDH1A1CYP3A4CYP1A2CYP2E1 | |
| SCHEMBL120088 | 0.71 | CYP2A6 (1.00) | CYP2A6ALDH1A1CYP3A4CYP1A2CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1630 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250361222-A1 | Extraction of nicotine from tobacco by closed cycle steam stripping and scrubbing | SAMULIS LEOPOLD (GB) | 2025-11-27 | — | — | US | claimed |
| EP-4651705-A1 | METHOD | Nicoventures Trading Limited (GB) | 2025-11-26 | — | — | EP | claimed |
| US-20250304984-A1 | METHOD OF MODULATING THE ALKALOID CONTENT OF TOBACCO | Nicoventures Trading Limited (GB) | 2025-10-02 | — | — | US | claimed |
| US-20250283103-A1 | METHOD OF MODULATING THE ALKALOID CONTENT OF TOBACCO | Nicoventures Trading Limited (GB) | 2025-09-11 | — | — | US | claimed |
| US-20250283101-A1 | METHOD OF MODULATING THE ALKALOID CONTENT OF TOBACCO | Nicoventures Trading Limited (GB) | 2025-09-11 | — | — | US | claimed |
| US-20250243499-A1 | METHOD OF MODULATING THE ALKALOID CONTENT OF TOBACCO | Nicoventures Trading Limited (GB) | 2025-07-31 | — | — | US | claimed |
| US-20250243500-A1 | METHOD FOR MODULATING THE ALKALOID CONTENT OF TOBACCO | Nicoventures Trading Limited (US) | 2025-07-31 | — | — | US | claimed |
| US-20250230457-A1 | METHOD OF MODULATING THE ALKALOID CONTENT OF TOBACCO | Nicoventures Trading Limited (GB) | 2025-07-17 | — | — | US | claimed |
| US-20250215443-A1 | METHOD OF MODULATING ALKALOID CONTENT IN TOBACCO PLANTS | Nicoventures Trading Limited (GB) | 2025-07-03 | — | — | US | claimed |
| CN-118005607-B | Process for the preparation of (S) -nicotine from myosmine | 扎诺普瑞玛生命科学有限公司 | 2025-06-17 | — | — | CN | claimed |
| EP-1675454-A1 | REDUCED-EXPOSURE TOBACCO PRODUCTS | 22nd Century Limitel, LLC (US) | 2006-07-05 | — | — | EP | claimed |
| WO-2005023942-A2 | MATERIALS AND METHODS FOR INHIBITING FOULING OF SURFACES EXPOSED TO AQUATIC ENVIRONMENTS | UNIVERSITY OF FLORIDA (US) | 2005-03-17 | — | — | WO | claimed |
| WO-2005018307-A1 | REDUCED-EXPOSURE TOBACCO PRODUCTS | 22ND CENTURY LIMITED, LLC (US) | 2005-03-03 | — | — | WO | claimed |
| US-20040235901-A1 | Materials and methods for inhibiting fouling of surfaces exposed to aquatic environments | DUKE UNIVERSITY | 2004-11-25 | — | — | US | claimed |
| US-5705512-A | COGNITION ACTIVATORS USING PYRROLIDINE PYRIDINE | SIBIA NEUROSCIENCES, INC. (US) | 1998-01-06 | — | — | US | claimed |
| EP-0567251-B1 | Treatment of neurodegenerative diseases | REYNOLDS TOBACCO CO R (US) | 1996-11-06 | — | — | EP | claimed |
| EP-0739342-A1 | PYRIDINE MODULATORS OF ACETYLCHOLINE RECEPTORS | SIBIA NEUROSCIENCES, INC. (US) | 1996-10-30 | — | — | EP | claimed |
| WO-1996015123-A1 | PYRIDINE MODULATORS OF ACETYLCHOLINE RECEPTORS | SIBIA NEUROSCIENCES, INC. (US) | 1996-05-23 | — | — | WO | claimed |
| US-5276043-A | Anabasine compounds | R. J. REYNOLDS TOBACCO COMPANY (US) | 1994-01-04 | — | — | US | claimed |
| EP-0567251-A1 | Treatment of neurodegenerative diseases | R.J. REYNOLDS TOBACCO COMPANY (US) | 1993-10-27 | — | — | EP | claimed |