Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.57 |
| ▸ | CETP | P11597 | 2/20 | 0.56 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5271392 | 0.89 | EP300 (0.69) | EP300CETPSOAT1HDAC3HDAC1 | |
| SCHEMBL1133527 | 0.89 | EP300 (0.69) | EP300CETPSOAT1HDAC3HDAC1 | |
| SCHEMBL8446067 | 0.89 | EP300 (0.69) | EP300CETPSOAT1HDAC3HDAC1 | |
| SCHEMBL3155514 | 0.89 | EP300 (0.69) | EP300CETPSOAT1HDAC3HDAC1 | |
| SCHEMBL28565040 | 0.89 | EP300 (0.69) | EP300CETPSOAT1HDAC3HDAC1 | |
| SCHEMBL14246925 | 0.89 | EP300 (0.69) | EP300CETPSOAT1HDAC3HDAC1 | |
| SCHEMBL28777021 | 0.89 | EP300 (0.69) | EP300CETPSOAT1HDAC3HDAC1 | |
| SCHEMBL1161259 | 0.89 | EP300 (0.69) | EP300CETPSOAT1HDAC3HDAC1 | |
| SCHEMBL6920533 | 0.89 | EP300 (0.69) | EP300CETPSOAT1HDAC3HDAC1 | |
| SCHEMBL18073904 | 0.86 | EP300 (0.48) | EP300CETPSOAT1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9242951-B2 | Covalent inhibition of bacterial quorum sensing | The National Institute for Biotechnology in the Negev Ltd. (IL) | 2016-01-26 | — | — | US | disclosed |
| US-9000190-B2 | Amide compound or salt thereof, biofilm inhibitor, biofilm remover and disinfectant containing the same | UNIVERSITY OF TOKYO (JP) | 2015-04-07 | — | — | US | disclosed |
| US-9000190-B2 | Amide compound or salt thereof, biofilm inhibitor, biofilm remover and disinfectant containing the same | UNIVERSITY OF TOKYO (JP) | 2015-04-07 | — | — | US | disclosed |
| US-20150018564-A1 | AMIDE COMPOUND OR SALT THEREOF, BIOFILM INHIBITOR, BIOFILM REMOVER AND DISINFECTANT CONTAINING THE SAME | UNIVERSITY OF TOKYO (JP) | 2015-01-15 | — | — | US | disclosed |
| US-20150018564-A1 | AMIDE COMPOUND OR SALT THEREOF, BIOFILM INHIBITOR, BIOFILM REMOVER AND DISINFECTANT CONTAINING THE SAME | UNIVERSITY OF TOKYO (JP) | 2015-01-15 | — | — | US | disclosed |
| US-8748617-B2 | Amide compound or salt thereof, and biofilm inhibitor, biofilm remover and disinfectant containing the same | UNIVERSITY OF TOKYO (JP) | 2014-06-10 | — | — | US | disclosed |
| US-8748617-B2 | Amide compound or salt thereof, and biofilm inhibitor, biofilm remover and disinfectant containing the same | UNIVERSITY OF TOKYO (JP) | 2014-06-10 | — | — | US | disclosed |
| US-20140073690-A1 | COVALENT INHIBITION OF BACTERIAL QUORUM SENSING | NAT INST FOR BIOTECHNOLOGY IN THE NEGEV LTD (IL) | 2014-03-13 | — | — | US | disclosed |
| US-8507674-B2 | Quorum sensing inhibitor | THE UNIVERSITY OF TOKYO (JP) | 2013-08-13 | — | — | US | disclosed |
| US-8507674-B2 | Quorum sensing inhibitor | THE UNIVERSITY OF TOKYO (JP) | 2013-08-13 | — | — | US | disclosed |
| US-20100256369-A1 | QUORUM SENSING INHIBITOR | THE UNIVERSITY OF TOKYO (JP) | 2010-10-07 | — | — | US | disclosed |
| US-20100256369-A1 | QUORUM SENSING INHIBITOR | THE UNIVERSITY OF TOKYO (JP) | 2010-10-07 | — | — | US | disclosed |
| EP-2215910-A1 | QUORUM SENSING INHIBITOR | The University of Tokyo (JP) | 2010-08-11 | — | — | EP | disclosed |
| EP-2100602-A1 | Method and compositions suitable for treatment of wounds | QuoNova Europe GmbH (DE) | 2009-09-16 | — | — | EP | disclosed |
| US-20090068120-A1 | AMIDE COMPOUND OR SALT THEREOF, AND BIOFILM INHIBITOR, BIOFILM REMOVER AND DISINFECTANT CONTAINING THE SAME | OTSUKA CHEMICAL CO., LTD. (JP) | 2009-03-12 | — | — | US | disclosed |
| US-20090068120-A1 | AMIDE COMPOUND OR SALT THEREOF, AND BIOFILM INHIBITOR, BIOFILM REMOVER AND DISINFECTANT CONTAINING THE SAME | OTSUKA CHEMICAL CO., LTD. (JP) | 2009-03-12 | — | — | US | disclosed |
| US-20080241081-A1 | AMIDE COMPOUND OR SALT THEREOF, AND BIOFILM REMOVER CONTAINING THE SAME | UNIVERSITY OF TOKYO (JP) | 2008-10-02 | — | — | US | disclosed |
| US-20080241081-A1 | AMIDE COMPOUND OR SALT THEREOF, AND BIOFILM REMOVER CONTAINING THE SAME | UNIVERSITY OF TOKYO (JP) | 2008-10-02 | — | — | US | disclosed |
| US-20080027115-A1 | COMBINATORIAL LIBRARIES OF AUTOINDUCER ANALOGS, AUTOINDUCER AGONISTS AND ANTAGONISTS, AND METHODS OF USE THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2008-01-31 | — | — | US | disclosed |
| US-20080027115-A1 | COMBINATORIAL LIBRARIES OF AUTOINDUCER ANALOGS, AUTOINDUCER AGONISTS AND ANTAGONISTS, AND METHODS OF USE THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150018564-A1 | AMIDE COMPOUND OR SALT THEREOF, BIOFILM INHIBITOR, BIOFILM REMOVER AND DISINFECTANT CONTAINING THE SAME | Q6ZSR9, F12, H1-0 | EP300 92/4885CETP 3973/4885SOAT1 423/4885 |
| US-20090068120-A1 | AMIDE COMPOUND OR SALT THEREOF, AND BIOFILM INHIBITOR, BIOFILM REMOVER AND DISINFECTANT CONTAINING THE SAME | Q6ZSR9, F12, H1-0 | EP300 86/4885CETP 4199/4885SOAT1 425/4885 |
| US-20080241081-A1 | AMIDE COMPOUND OR SALT THEREOF, AND BIOFILM REMOVER CONTAINING THE SAME | H1-0, H1-10, H1-4 | EP300 133/4885CETP 1381/4885SOAT1 717/4885 |
| US-20140073690-A1 | COVALENT INHIBITION OF BACTERIAL QUORUM SENSING | BLVRB, DBI, COASY | EP300 841/4885CETP 2895/4885SOAT1 921/4885 |
| US-20080027115-A1 | COMBINATORIAL LIBRARIES OF AUTOINDUCER ANALOGS, AUTOINDUCER AGONISTS AND ANTAGONISTS, AND METHODS OF USE THEREOF | QRFPR, CASR, BLVRB | EP300 3465/4885CETP 4423/4885SOAT1 1388/4885 |
| US-20100256369-A1 | QUORUM SENSING INHIBITOR | BLVRB, API5, Q6ZSR9 | EP300 3678/4885CETP 4286/4885SOAT1 1542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.