Sugi Predict

Sugi Predict / Compounds / Tryptophan

Tryptophan

Tryptophan

SCHEMBL120930

N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.89
▸ KDM4E B2RXH2 3/20 0.89
▸ MAPT P10636 3/20 0.89
▸ MEN1 O00255 2/20 0.89
▸ LMNA P02545 2/20 0.89
▸ TSHR P16473 2/20 0.89
▸ BLM P54132 2/20 0.89
▸ PMP22 Q01453 2/20 0.89
▸ MPO P05164 1/20 0.89
▸ HIF1A Q16665 1/20 0.89
▸ SMN1; SMN2 Q16637 1/20 0.63
▸ HSP90AA1 P07900 1/20 0.63
▸ HSP90AB1 P08238 1/20 0.63
▸ LTA4H P09960 1/20 0.63
▸ PLA2G2A P14555 1/20 0.63
▸ APAF1 O14727 1/20 0.62
▸ POLB P06746 1/20 0.62
▸ RECQL P46063 1/20 0.62
▸ L3MBTL1 Q9Y468 1/20 0.62
▸ HTR1A P08908 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Tryptophan SCHEMBL27641165 1.00 KMT2A (0.89) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL120929 1.00 KMT2A (0.89) KMT2AKDM4EMAPTMEN1LMNA
D-Tryptophan SCHEMBL11869971 1.00 KMT2A (0.89) KMT2AKDM4EMAPTMEN1LMNA
Tryptophan SCHEMBL6046200 0.95 KMT2A (0.80) KMT2AKDM4EMAPTMEN1LMNA
Tryptophan SCHEMBL23141133 0.94 KMT2A (1.00) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL475349 0.94 KMT2A (1.00) KMT2AKDM4EMAPTMEN1LMNA
Tryptophan SCHEMBL475350 0.94 KMT2A (1.00) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL19161120 0.94 KMT2A (1.00) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL7327 0.94 KMT2A (1.00) KMT2AKDM4EMAPTMEN1LMNA
Tryptophan SCHEMBL4732053 0.94 KMT2A (1.00) KMT2AKDM4EMAPTMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1047 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113629183-B Phenylalanine dipeptidyl co-self-assembled product and preparation method and application thereof 西安电子科技大学 2023-09-05 — — CN claimed
CN-116284216-A Aromatic dipeptide functionalized sulfhydryl compound and preparation method and application thereof 华能武汉发电有限责任公司 2023-06-23 — — CN claimed
CN-113514518-B Preparation method of hydrogen peroxide sensor based on polypeptide-enzyme composite material 江苏大学 2023-05-09 — — CN claimed
CN-115746089-A Allyl alcohol derivatives and their use in protein modification 国科大杭州高等研究院 2023-03-07 — — CN claimed
CN-113629183-A Phenylalanine dipeptide-based co-self-assembly product and preparation method and application thereof 西安电子科技大学 2021-11-09 — — CN claimed
CN-113514518-A Preparation method of hydrogen peroxide sensor based on polypeptide-enzyme composite material 江苏大学 2021-10-19 — — CN claimed
CN-112641956-A Preparation and application of peptide-metal-drug self-assembly nanoparticles for resisting Alzheimer's disease 福州大学 2021-04-13 — — CN claimed
CN-109156824-A A kind of preoperative special meals drink and the preparation method and application thereof taken of diabetes patient 广州钮和生物科技有限公司 2019-01-08 — — CN claimed
US-9230708-B2 Self assembly of naphthalene diimide derivatives and process thereof JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) 2016-01-05 — — US claimed
US-20150159144-A1 ENZYME VARIANTS WITH IMPROVED PROPERTIES METGEN OY (FI) 2015-06-11 — — US claimed
EP-2756076-A1 ENZYME VARIANTS WITH IMPROVED PROPERTIES MetGen Oy (FI) 2014-07-23 — — EP claimed
US-20130302587-A1 SELF ASSEMBLY OF NAPHTHALENE DIIMIDE DERIVATES AND PROCESS THEREOF JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) 2013-11-14 — — US claimed
WO-2013038062-A1 ENZYME VARIANTS WITH IMPROVED PROPERTIES METGEN OY (FI) 2013-03-21 — — WO claimed
US-20130012457-A1 BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING THE UNIVERSITY OF LEEDS 2013-01-10 — — US claimed
WO-2012098439-A1 SELF ASSEMBLY OF NAPHTHALENE DIIMIDE DERIVATIVES AND PROCESS THEREOF JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) 2012-07-26 — — WO claimed
EP-2364991-A1 A process for the preparation of poly-alfa-glutamic acid and derivatives thereof Cell Therapeutics, Inc. - Sede Secondaria (IT) 2011-09-14 — — EP claimed
EP-2027145-A1 A PROCESS FOR THE PREPARATION OF POLY-ALFA-GLUTAMIC ACID AND DERIVATIVES THEREOF Cell Therapeutics, Inc. - Sede Secondaria (IT) 2009-02-25 — — EP claimed
WO-2007144140-A1 A PROCESS FOR THE PREPARATION OF POLY-ALFA-GLUTAMIC ACID AND DERIVATIVES THEREOF CELL THERAPEUTICS INC. - SEDE SECONDARIA (IT) 2007-12-21 — — WO claimed
WO-2024081692-A1 MITHRAMYCIN OXIME DERIVATIVES HAVING INCREASED SELECTIVITY AND ANTI-CANCER ACTIVITY UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2024-04-18 — — WO disclosed
EP-0173233-A2 Chromatographic method and means PURDUE RESEARCH FOUNDATION (US) 1986-03-05 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130012457-A1 BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING IAPP, TAGLN2, KRT18 KMT2A 4472/4885KDM4E 4717/4885MAPT 152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.