Dl-Tryptophan

Dl-Tryptophan

SCHEMBL120929

NC(Cc1c[nH]c2ccccc12)C(=O)O.NC(Cc1ccccc1)C(=O)O

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.89
KDM4E B2RXH2 3/20 0.89
MAPT P10636 3/20 0.89
MEN1 O00255 2/20 0.89
LMNA P02545 2/20 0.89
TSHR P16473 2/20 0.89
BLM P54132 2/20 0.89
PMP22 Q01453 2/20 0.89
MPO P05164 1/20 0.89
HIF1A Q16665 1/20 0.89
SMN1; SMN2 Q16637 1/20 0.63
HSP90AA1 P07900 1/20 0.63
HSP90AB1 P08238 1/20 0.63
LTA4H P09960 1/20 0.63
PLA2G2A P14555 1/20 0.63
APAF1 O14727 1/20 0.62
POLB P06746 1/20 0.62
RECQL P46063 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
HTR1A P08908 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Tryptophan SCHEMBL27641165 1.00 KMT2A (0.89) KMT2AKDM4EMAPTMEN1LMNA
Tryptophan SCHEMBL120930 1.00 KMT2A (0.89) KMT2AKDM4EMAPTMEN1LMNA
D-Tryptophan SCHEMBL11869971 1.00 KMT2A (0.89) KMT2AKDM4EMAPTMEN1LMNA
Tryptophan SCHEMBL6046200 0.95 KMT2A (0.80) KMT2AKDM4EMAPTMEN1LMNA
Tryptophan SCHEMBL23141133 0.94 KMT2A (1.00) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL475349 0.94 KMT2A (1.00) KMT2AKDM4EMAPTMEN1LMNA
Tryptophan SCHEMBL475350 0.94 KMT2A (1.00) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL19161120 0.94 KMT2A (1.00) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL7327 0.94 KMT2A (1.00) KMT2AKDM4EMAPTMEN1LMNA
Tryptophan SCHEMBL4732053 0.94 KMT2A (1.00) KMT2AKDM4EMAPTMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1034 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113514518-B Preparation method of hydrogen peroxide sensor based on polypeptide-enzyme composite material 江苏大学 2023-05-09 CN claimed
CN-115746089-A Allyl alcohol derivatives and their use in protein modification 国科大杭州高等研究院 2023-03-07 CN claimed
CN-113533279-B Method for detecting enrofloxacin by using fluorescent dipeptide nano microspheres/nucleic acid aptamer 河北农业大学 2022-07-29 CN claimed
CN-114182358-A Anti-tau protein fluorescent polypeptide nanoparticle array, preparation method and application 西北工业大学 2022-03-15 CN claimed
CN-111249469-B Peptide nanoparticle capable of escaping lysosome and preparation method and application thereof 临沂大学 2022-03-08 CN claimed
CN-113533279-A Method for detecting enrofloxacin by using fluorescent dipeptide nano microspheres/nucleic acid aptamer 河北农业大学 2021-10-22 CN claimed
CN-113514518-A Preparation method of hydrogen peroxide sensor based on polypeptide-enzyme composite material 江苏大学 2021-10-19 CN claimed
WO-2020204317-A1 METHOD FOR INDUCING DIFFERENTIATION OF STEM CELLS INTO CHONDROCYTES BY USING OLIGOPEPTIDES 이화여자대학교 산학협력단 2020-10-08 WO claimed
CN-111249469-A Peptide nanoparticle capable of escaping lysosome and preparation method and application thereof 临沂大学 2020-06-09 CN claimed
CN-109156824-A A kind of preoperative special meals drink and the preparation method and application thereof taken of diabetes patient 广州钮和生物科技有限公司 2019-01-08 CN claimed
US-20130012457-A1 BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING THE UNIVERSITY OF LEEDS 2013-01-10 US claimed
EP-2364991-A1 A process for the preparation of poly-alfa-glutamic acid and derivatives thereof Cell Therapeutics, Inc. - Sede Secondaria (IT) 2011-09-14 EP claimed
EP-2027145-A1 A PROCESS FOR THE PREPARATION OF POLY-ALFA-GLUTAMIC ACID AND DERIVATIVES THEREOF Cell Therapeutics, Inc. - Sede Secondaria (IT) 2009-02-25 EP claimed
WO-2007144140-A1 A PROCESS FOR THE PREPARATION OF POLY-ALFA-GLUTAMIC ACID AND DERIVATIVES THEREOF CELL THERAPEUTICS INC. - SEDE SECONDARIA (IT) 2007-12-21 WO claimed
US-20240043561-A1 HUMANIZED ANTIBODIES AND FRAGMENTS THEREOF BINDING TO CARBOHYDRATE ANTIGENS AND USES THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2024-02-08 US disclosed
CN-117482145-A Traditional Chinese medicine extract, preparation method thereof and application thereof in preparation of medicine for treating Alzheimer's disease 中国科学院长春应用化学研究所 2024-02-02 CN disclosed
US-11884714-B2 Cyclic peptide analogs of melanocortin and amanitin and methods of making such THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2024-01-30 US disclosed
CN-1049165-A The cycloalkyl that N-replaces and the tryptophane-phenylalanine of multi-ring alkyl alpha-substitution-and phenylethylamine derivative WARNER LAMBERT CO (US) 1991-02-13 CN disclosed
CN-1049165-A The cycloalkyl that N-replaces and the tryptophane-phenylalanine of multi-ring alkyl alpha-substitution-and phenylethylamine derivative WARNER LAMBERT CO (US) 1991-02-13 CN disclosed
CN-1049165-A The cycloalkyl that N-replaces and the tryptophane-phenylalanine of multi-ring alkyl alpha-substitution-and phenylethylamine derivative WARNER LAMBERT CO (US) 1991-02-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11884714-B2 Cyclic peptide analogs of melanocortin and amanitin and methods of making such MC3R, MC5R, MC4R KMT2A 3454/4885KDM4E 3918/4885MAPT 1427/4885
US-20240043561-A1 HUMANIZED ANTIBODIES AND FRAGMENTS THEREOF BINDING TO CARBOHYDRATE ANTIGENS AND USES THEREOF CD47, FCGR2A, FCGR3B KMT2A 496/4885KDM4E 3096/4885MAPT 2344/4885
US-20130012457-A1 BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING IAPP, TAGLN2, KRT18 KMT2A 4472/4885KDM4E 4717/4885MAPT 152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.