SCHEMBL12094803

SCHEMBL12094803

CCCC[C@H](NC(C)=O)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O

nearest known ligand 0.62

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 5/20 0.62
▸ KISS1R Q969F8 11/20 0.58
▸ CCKBR P32239 2/20 0.58
▸ IL23R Q5VWK5 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12094761 1.00 MC4R (0.62) MC4RKISS1RCCKBRIL23R
SCHEMBL12094763 1.00 MC4R (0.62) MC4RKISS1RCCKBRIL23R
SCHEMBL12094740 1.00 MC4R (0.62) MC4RKISS1RCCKBRIL23R
SCHEMBL12094778 1.00 MC4R (0.62) MC4RKISS1RCCKBRIL23R
SCHEMBL12094739 0.97 MC4R (0.59) MC4RKISS1RCCKBRIL23R
SCHEMBL12094775 0.97 IL23R (0.59) MC4RKISS1RCCKBRIL23R
SCHEMBL12094766 0.97 IL23R (0.62) MC4RKISS1RIL23R
SCHEMBL18556748 0.95 CCKBR (0.64) MC4RKISS1RCCKBRIL23R
SCHEMBL29476543 0.93 MC4R (0.68) MC4RKISS1R
SCHEMBL12094757 0.93 MC4R (0.58) MC4RKISS1RCCKBRIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170145056-A1 Melanocortin-1 Receptor-Specific Linear Peptides PALATIN TECHNOLOGIES INC (US) 2017-05-25 — — US disclosed
US-9580466-B2 Melanocortin-1 receptor-specific linear peptides PALATIN TECHNOLOGIES, INC. (US) 2017-02-28 — — US disclosed
US-20150119341-A1 Melanocortin-1 Receptor-Specific Linear Peptides PALATIN TECHNOLOGIES INC (US) 2015-04-30 — — US disclosed
US-8933194-B2 Melanocortin-1 receptor-specific linear peptides PALATIN TECHNOLOGIES, INC. (US) 2015-01-13 — — US disclosed
US-20120225831-A1 Melanocortin-1 Receptor-Specific Linear Peptides PALATIN TECHNOLOGIES, INC. (US) 2012-09-06 — — US disclosed
WO-2011063367-A1 MELANOCORTIN-1 RECEPTOR-SPECIFIC LINEAR PEPTIDES PALATIN TECHNOLOGIES, INC. (US) 2011-05-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170145056-A1 Melanocortin-1 Receptor-Specific Linear Peptides MC1R, MC5R, MC3R MC4R 4/4885KISS1R 188/4885CCKBR 71/4885
US-20150119341-A1 Melanocortin-1 Receptor-Specific Linear Peptides MC1R, MC3R, MC5R MC4R 4/4885KISS1R 93/4885CCKBR 81/4885
US-20120225831-A1 Melanocortin-1 Receptor-Specific Linear Peptides MC1R, MC3R, MC5R MC4R 4/4885KISS1R 93/4885CCKBR 81/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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