Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12096372 | 0.86 | ALDH1A1 (0.37) | TP53 | |
| SCHEMBL20456079 | 0.73 | — | — | |
| SCHEMBL17026446 | 0.73 | OR51E2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL22558277 | 0.71 | — | — | |
| SCHEMBL16195019 | 0.69 | GRM1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL16195009 | 0.69 | SLC1A3 (0.31) | — | |
| SCHEMBL22028163 | 0.67 | GRIK1 (0.31) | CYP2C19 | |
| Phosphoric Acid SCHEMBL22558289 | 0.67 | — | — | |
| Succinic Acid SCHEMBL22558275 | 0.66 | EGLN1 (0.36) | — | |
| SCHEMBL19747747 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2497470-A1 | Imidazotriazines and imidazopyrimidines as kinase inhibitors | Incyte Corporation (US) | 2012-09-12 | — | — | EP | disclosed |