Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.40 |
| ▸ | F10 | P00742 | 6/20 | 0.40 |
| ▸ | F9 | P00740 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 2/20 | 0.39 |
| ▸ | PLAT | P00750 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12095939 | 0.90 | F2 (0.44) | F2F10F9PLGPLAT | |
| SCHEMBL1770855 | 0.89 | F2 (0.42) | F2F10F9PLGPLAT | |
| SCHEMBL12095840 | 0.88 | F2 (0.48) | F2F10F9PLGPLAT | |
| SCHEMBL12095931 | 0.87 | F2 (0.51) | F2F10F9PLGPLAT | |
| SCHEMBL12095719 | 0.86 | F2 (0.40) | F2F10F9PLGPLAT | |
| SCHEMBL12095910 | 0.85 | F2 (0.51) | F2F10F9PLGPLAT | |
| SCHEMBL12096455 | 0.85 | F2 (0.41) | F2F10F9PLGPLAT | |
| SCHEMBL12096171 | 0.85 | F2 (0.42) | F2F10F9PLGPLAT | |
| SCHEMBL12095711 | 0.85 | F10 (0.44) | F2F10F9PLGPLAT | |
| SCHEMBL12095717 | 0.84 | F2 (0.43) | F2F10F9PLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254881-B1 | CHLOROTHIOPHENE-AMIDES AS INHIBITORS OF COAGULATION FACTORS XA AND THROMBIN | SANOFI SA (FR) | 2012-09-12 | — | — | EP | disclosed |