Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 15/20 | 0.51 |
| ▸ | F10 | P00742 | 13/20 | 0.51 |
| ▸ | F9 | P00740 | 2/20 | 0.44 |
| ▸ | PLG | P00747 | 2/20 | 0.44 |
| ▸ | PLAT | P00750 | 2/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12095931 | 0.90 | F2 (0.51) | F2F10F9PLGPLAT | |
| SCHEMBL12095911 | 0.89 | F2 (0.56) | F2F10F9PLGPLAT | |
| SCHEMBL12096009 | 0.88 | F2 (0.54) | F2F10F9PLGPLAT | |
| SCHEMBL1770239 | 0.88 | F2 (0.50) | F2F10F9PLGPLAT | |
| Trifluoroacetic Acid SCHEMBL3401451 | 0.86 | F2 (0.60) | F2F10F9PLGPLAT | |
| SCHEMBL12095938 | 0.85 | F2 (0.40) | F2F10F9PLGPLAT | |
| SCHEMBL1770847 | 0.85 | F2 (0.53) | F2F10F9PLGPLAT | |
| SCHEMBL12095852 | 0.85 | F2 (0.55) | F2F10F9PLGPLAT | |
| SCHEMBL3404400 | 0.84 | F2 (0.51) | F2F10F9PLGPLAT | |
| SCHEMBL12096329 | 0.84 | F2 (0.52) | F2F10F9PLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254881-B1 | CHLOROTHIOPHENE-AMIDES AS INHIBITORS OF COAGULATION FACTORS XA AND THROMBIN | SANOFI SA (FR) | 2012-09-12 | — | — | EP | disclosed |