Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6673958 | 1.00 | PYGB (0.48) | PYGBGAA | |
| SCHEMBL3642848 | 0.80 | PYGB (0.53) | PYGBGAA | |
| SCHEMBL1211367 | 0.80 | PYGB (0.53) | PYGBGAA | |
| SCHEMBL30957909 | 0.77 | PYGB (0.69) | PYGBGAA | |
| SCHEMBL4307948 | 0.75 | PYGB (0.62) | PYGBGAA | |
| SCHEMBL6674516 | 0.74 | PYGB (0.60) | PYGBGAA | |
| SCHEMBL4093489 | 0.73 | PYGB (0.59) | PYGBGAA | |
| SCHEMBL4093481 | 0.73 | PYGB (0.59) | PYGBGAA | |
| SCHEMBL6672246 | 0.72 | PYGB (0.63) | PYGBGAA | |
| SCHEMBL6673962 | 0.71 | PYGB (0.50) | PYGBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110288042-A1 | STABLE HIGHLY PURE AZACITIDINE AND PREPARATION METHODS THEREFOR | CHEMAGIS LTD. (IL) | 2011-11-24 | — | — | US | claimed |
| US-20110042247-A1 | FORMULATIONS OF AZACITIDINE AND ITS DERIVATIVES | DR. REDDY'S LABORATORIES LIMITED (IN) | 2011-02-24 | — | — | US | claimed |
| EP-2176279-A2 | STABLE HIGHLY PURE AZACITIDINE AND PREPARATION METHODS THEREFOR | Chemagis Ltd. (IL) | 2010-04-21 | — | — | EP | claimed |
| WO-2009016617-A2 | STABLE HIGHLY PURE AZACITIDINE AND PREPARATION METHODS THEREFOR | CHEMAGIS LTD. (IL) | 2009-02-05 | — | — | WO | claimed |
| US-9951098-B2 | Synthesis of 5-azacytidine | PHARMION LLC (US) | 2018-04-24 | — | — | US | disclosed |
| US-9765108-B2 | Formulation of 5-azacytidine | SHILPA MEDICARE LIMITED | 2017-09-19 | — | — | US | disclosed |
| EP-2691408-B1 | SYNTHESIS OF 5-AZACYTIDINE | CELGENE INT SÁRL (CH) | 2017-06-28 | — | — | EP | disclosed |
| US-20160095925-A1 | STABLE FORMULATION OF AZACITIDINE OR SALTS THEREOF AND THEIR PROCESS FOR PREPARATION | CADILA HEALTHCARE LIMITED (IN) | 2016-04-07 | — | — | US | disclosed |
| US-20150284421-A1 | FORMULATION OF 5-AZACYTIDINE | SHILPA MEDICARE LIMITED (IN) | 2015-10-08 | — | — | US | disclosed |
| WO-2014076616-A2 | FORMULATIONS OF 5-AZACYTIDINE | SHILPA MEDICARE LIMITED (IN) | 2014-05-22 | — | — | WO | disclosed |
| US-20140128593-A1 | SYNTHESIS OF 5-AZACYTIDINE | CELGENE INTERNATIONAL SARL (US) | 2014-05-08 | — | — | US | disclosed |
| US-20110288042-A1 | STABLE HIGHLY PURE AZACITIDINE AND PREPARATION METHODS THEREFOR | CHEMAGIS LTD. (IL) | 2011-11-24 | — | — | US | disclosed |
| US-20110042247-A1 | FORMULATIONS OF AZACITIDINE AND ITS DERIVATIVES | DR. REDDY'S LABORATORIES LIMITED (IN) | 2011-02-24 | — | — | US | disclosed |
| EP-2176279-A2 | STABLE HIGHLY PURE AZACITIDINE AND PREPARATION METHODS THEREFOR | Chemagis Ltd. (IL) | 2010-04-21 | — | — | EP | disclosed |
| WO-2009016617-A2 | STABLE HIGHLY PURE AZACITIDINE AND PREPARATION METHODS THEREFOR | CHEMAGIS LTD. (IL) | 2009-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160095925-A1 | STABLE FORMULATION OF AZACITIDINE OR SALTS THEREOF AND THEIR PROCESS FOR PREPARATION | AZI2, PAICS, ITPA | PYGB 2643/4885GAA 999/4885 |
| US-20110042247-A1 | FORMULATIONS OF AZACITIDINE AND ITS DERIVATIVES | AZI2, TP53, TET2 | PYGB 4663/4885GAA 1121/4885 |
| US-20110288042-A1 | STABLE HIGHLY PURE AZACITIDINE AND PREPARATION METHODS THEREFOR | UNG, DCTD, CDA | PYGB 3054/4885GAA 733/4885 |
| US-20150284421-A1 | FORMULATION OF 5-AZACYTIDINE | AZI2, DPYD, DCTD | PYGB 4005/4885GAA 401/4885 |
| US-20140128593-A1 | SYNTHESIS OF 5-AZACYTIDINE | AZI2, TET2, DNMT1 | PYGB 4435/4885GAA 1406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.