Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4677350 | 0.84 | TSHR (0.37) | TSHRALDH1A1CYP3A4TDP1MAPT | |
| SCHEMBL4677345 | 0.82 | TSHR (0.38) | TSHRALDH1A1CYP3A4TDP1MAPT | |
| SCHEMBL9073802 | 0.80 | THRB (0.44) | TSHRALDH1A1THRBCYP3A4 | |
| SCHEMBL26945317 | 0.80 | TSHR (0.41) | TSHRALDH1A1CYP3A4TDP1MAPT | |
| SCHEMBL10012845 | 0.80 | TSHR (0.37) | TSHRALDH1A1CYP3A4TDP1MAPT | |
| SCHEMBL28184314 | 0.79 | TSHR (0.48) | TSHRALDH1A1THRBCYP3A4TDP1 | |
| SCHEMBL4676427 | 0.77 | TSHR (0.35) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL7817361 | 0.77 | TSHR (0.39) | TSHRCYP3A4TDP1MAPTCACNA1B | |
| SCHEMBL10011984 | 0.77 | SMN1; SMN2 (0.36) | TSHRALDH1A1CYP3A4TDP1MAPT | |
| SCHEMBL4676431 | 0.77 | TSHR (0.42) | TSHRALDH1A1CYP3A4TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2520579-B1 | A silicone compound, photocurable liquid ink using the silicone compound, and method of manufacturing the ink | RICOH CO LTD (JP) | 2015-08-05 | — | — | EP | disclosed |
| US-20120232222-A1 | METHOD FOR PRODUCING 1-ALKOXY-2-METHYL-1-OXOPROPAN-2-YL (METH)ACRYLATE | EVONIK ROEHM GMBH (DE) | 2012-09-13 | — | — | US | disclosed |