SCHEMBL12100930

SCHEMBL12100930

CCNc1ncccc1Nc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 2/20 0.48
DHODH Q02127 1/20 0.45
CYP1A2 P05177 3/20 0.42
CYP2D6 P10635 3/20 0.42
CYP2C9 P11712 3/20 0.42
CYP2C19 P33261 3/20 0.42
HPGD P15428 3/20 0.42
CYP3A4 P08684 1/20 0.42
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
ALDH1A1 P00352 4/20 0.42
GAA P10253 3/20 0.42
MAPT P10636 3/20 0.42
HTT P42858 2/20 0.42
KDM4E B2RXH2 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
UTS2R Q9UKP6 1/20 0.40
GLA P06280 1/20 0.40
RECQL P46063 1/20 0.40
GRM4 Q14833 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20484330 0.91 MAPT (0.47) GRM5DHODHCYP1A2CYP2D6CYP2C9
SCHEMBL6689566 0.82 DHODH (0.58) DHODHCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL12172562 0.81 DHODH (0.49) DHODHCYP1A2CYP2D6CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL14672810 0.80 DHODH (0.56) DHODHCYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL18951516 0.80 MEN1 (0.52) DHODHMEN1KMT2AALDH1A1GAA
SCHEMBL1746368 0.79 GRM5 (0.49) GRM5CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL29734989 0.76 MAPT (0.50) CYP1A2CYP2D6CYP2C9CYP2C19HPGD
SCHEMBL6318646 0.76 MAPT (0.50) CYP1A2CYP2D6CYP2C9CYP2C19HPGD
SCHEMBL12172496 0.74 DHODH (0.53) DHODHMEN1KMT2AALDH1A1GAA
SCHEMBL17154865 0.73 SLC2A1 (0.51) DHODHCYP1A2CYP2D6CYP2C19CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11600791-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-03-07 US disclosed
EP-3936512-A1 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS Universal Display Corporation (US) 2022-01-12 EP disclosed
EP-3936512-A1 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS Universal Display Corporation (US) 2022-01-12 EP disclosed
EP-3424935-B1 IMIDAZOPYRAZINYL CARBENE PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORP (US) 2021-08-11 EP disclosed
EP-3424935-B1 IMIDAZOPYRAZINYL CARBENE PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORP (US) 2021-08-11 EP disclosed
US-20210050530-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-02-18 US disclosed
US-20210050530-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-02-18 US disclosed
US-10873038-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-12-22 US disclosed
US-10873038-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-12-22 US disclosed
US-20190109287-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-04-11 US disclosed
US-20150021590-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-01-22 US disclosed
US-20150021590-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-01-22 US disclosed
US-20150021590-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-01-22 US disclosed
US-8883322-B2 Pyridyl carbene phosphorescent emitters UNIVERSAL DISPLAY CORPORATION (US) 2014-11-11 US disclosed
US-8883322-B2 Pyridyl carbene phosphorescent emitters UNIVERSAL DISPLAY CORPORATION (US) 2014-11-11 US disclosed
US-8883322-B2 Pyridyl carbene phosphorescent emitters UNIVERSAL DISPLAY CORPORATION (US) 2014-11-11 US disclosed
US-20120228583-A1 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2012-09-13 US disclosed
US-20120228583-A1 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2012-09-13 US disclosed
US-20120228583-A1 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2012-09-13 US disclosed
WO-2012121936-A2 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2012-09-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210050530-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NUDC, NCL, NDC1 GRM5 3022/4885DHODH 4003/4885CYP1A2 3094/4885
US-10873038-B2 Organic electroluminescent materials and devices NUDC, NCL, NDC1 GRM5 3022/4885DHODH 4003/4885CYP1A2 3094/4885
US-20120228583-A1 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS PAICS, PIR, NUDC GRM5 3558/4885DHODH 3893/4885CYP1A2 2838/4885
US-20190109287-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NUDC, NCL, NDC1 GRM5 3022/4885DHODH 4003/4885CYP1A2 3094/4885
US-11600791-B2 Organic electroluminescent materials and devices NUDC, NCL, NDC1 GRM5 3022/4885DHODH 4003/4885CYP1A2 3094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.