SCHEMBL6318646

SCHEMBL6318646

CCNc1ccccc1Nc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.50
GAA P10253 4/20 0.50
TDP1 Q9NUW8 4/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
KDM4E B2RXH2 2/20 0.50
GLA P06280 1/20 0.50
RECQL P46063 1/20 0.50
ALDH1A1 P00352 6/20 0.48
LMNA P02545 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
HSD17B10 Q99714 3/20 0.46
FABP4 P15090 2/20 0.46
ALOX15 P16050 3/20 0.45
TSHR P16473 2/20 0.45
HPGD P15428 2/20 0.45
TP53 P04637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29734989 1.00 MAPT (0.50) MAPTGAATDP1MEN1KMT2A
SCHEMBL29813222 0.83 MAPT (0.47) MAPTGAATDP1MEN1KMT2A
SCHEMBL809569 0.83 MAPT (0.47) MAPTGAATDP1MEN1KMT2A
SCHEMBL526384 0.83 IDO1 (0.52) MAPTTDP1MEN1KMT2ARECQL
Hydrochloric Acid SCHEMBL5804938 0.81 IDO1 (0.50) MAPTTDP1MEN1KMT2ARECQL
Iodide SCHEMBL27185482 0.81 IDO1 (0.50) MAPTTDP1MEN1KMT2ARECQL
SCHEMBL444976 0.81 MAPT (0.70) MAPTGAATDP1MEN1KMT2A
SCHEMBL6687184 0.80 KCNH3 (0.54) MAPTGAATDP1MEN1KMT2A
SCHEMBL29734978 0.80 KCNH3 (0.54) MAPTGAATDP1MEN1KMT2A
SCHEMBL1851554 0.79 KCNH3 (0.61) MAPTGAATDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6914098-B2 Acrylic elastomer and its composition NIPPON MEKIRON, LIMITED (JP) 2005-07-05 US disclosed
US-20040087729-A1 Acrylic elastomer and its composition MORIYAMA IWAO (JP) 2004-05-06 US disclosed
US-20040019154-A1 Acrylic elastomer and its composition MORIYAMA IWAO (JP) 2004-01-29 US disclosed
EP-1078973-B1 Stabilised monomer composition ROEHM GMBH (DE) 2002-11-27 EP disclosed
US-20010005742-A1 Acrylic elastomer and its composition NIPPON MEKTRON, LIMITED 2001-06-28 US disclosed
EP-1110980-A1 Acrylic elastomer and its composition Nippon Mektron, Limited (JP) 2001-06-27 EP disclosed
US-6015860-A POLYFUNCTIONAL (BLOCKED) ISOCYANATE, GUANIDINE, QUATERNARY AMMONIUM SALT, TERTIARY AMINE, AND TERTIARY PHOSPHINE VULCANIZATION ACCELERATOR; HEAT AND SCORCH RESISTANCE; RESILIENCE NIPPON MEKTRON, LIMITED (JP) 2000-01-18 US disclosed
EP-0905163-A1 Acrylic elastomer composition Nippon Mektron, Limited (JP) 1999-03-31 EP disclosed