Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 17/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 9/20 | 0.47 |
| ▸ | DRD2 | P14416 | 8/20 | 0.47 |
| ▸ | DRD3 | P35462 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12100989 | 0.90 | ADRB2 (0.43) | ADRB2CHRM3ADRB1 | |
| SCHEMBL10241857 | 0.90 | ADRB2 (0.65) | ADRB2CHRM3ADRB1ADRA1DDRD2 | |
| SCHEMBL12100993 | 0.89 | ADRB2 (0.59) | ADRB2CHRM3ADRB1ADRA1DDRD2 | |
| SCHEMBL12100988 | 0.82 | ADRB2 (0.46) | ADRB2CHRM3ADRB1ADRA1DDRD2 | |
| SCHEMBL10241864 | 0.81 | ADRB2 (0.54) | ADRB2CHRM3ADRB1 | |
| SCHEMBL10241697 | 0.81 | ADRB2 (0.73) | ADRB2CHRM3ADRB1ADRA1DDRD2 | |
| SCHEMBL10241745 | 0.80 | ADRB2 (0.68) | ADRB2CHRM3ADRB1ADRA1DDRD2 | |
| SCHEMBL12100983 | 0.79 | ADRB2 (0.53) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL12100991 | 0.79 | ADRB2 (0.53) | ADRB2ADRB1ADRA1DDRD2DRD3 | |
| SCHEMBL10241995 | 0.77 | ADRB2 (0.66) | ADRB2CHRM3ADRB1ADRA1DDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242759-B1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2012-09-12 | — | — | EP | disclosed |