Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 6/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 13/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1245055 | 0.89 | CHRM2 (0.54) | CHRM2CHRM3CYP3A4CYP2D6USP2 | |
| SCHEMBL2140513 | 0.86 | CHRM3 (0.68) | CHRM2CHRM3 | |
| SCHEMBL12101058 | 0.86 | CHRM2 (0.53) | CHRM2CHRM3CYP3A4CYP2D6USP2 | |
| SCHEMBL12101033 | 0.81 | CHRM2 (0.56) | CHRM2CHRM3CYP3A4CYP2D6USP2 | |
| SCHEMBL12101065 | 0.79 | CHRM2 (0.50) | CHRM2CHRM3CYP3A4CYP2D6USP2 | |
| SCHEMBL2141151 | 0.76 | CHRM3 (0.67) | CHRM2CHRM3 | |
| SCHEMBL12101023 | 0.75 | CYP3A4 (0.42) | CHRM2CHRM3CYP3A4CYP2D6USP2 | |
| SCHEMBL12101012 | 0.75 | CHRM2 (0.56) | CHRM2CHRM3CYP3A4CYP2D6USP2 | |
| SCHEMBL1246077 | 0.75 | CHRM3 (0.74) | CHRM2CHRM3 | |
| SCHEMBL12101073 | 0.74 | CHRM2 (0.45) | CHRM2CHRM3CYP3A4CYP2D6USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242759-B1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2012-09-12 | — | — | EP | disclosed |