Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 9/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12101012 | 0.91 | CHRM2 (0.56) | CHRM2CHRM3CYP3A4TSHRCYP1A2 | |
| SCHEMBL2139669 | 0.86 | CHRM2 (0.76) | CHRM2CHRM3 | |
| SCHEMBL12101065 | 0.84 | CHRM2 (0.50) | CHRM2CHRM3CYP3A4TSHRCYP1A2 | |
| SCHEMBL1245055 | 0.83 | CHRM2 (0.54) | CHRM2CHRM3CYP3A4TSHRCYP1A2 | |
| SCHEMBL12100997 | 0.81 | CHRM2 (0.49) | CHRM2CHRM3CYP3A4TSHRCYP1A2 | |
| SCHEMBL2140718 | 0.80 | CHRM2 (0.77) | CHRM2CHRM3 | |
| SCHEMBL12101058 | 0.80 | CHRM2 (0.53) | CHRM2CHRM3CYP3A4TSHRCYP1A2 | |
| SCHEMBL12101098 | 0.78 | CHRM2 (0.50) | CHRM2CHRM3CYP3A4TSHRCYP1A2 | |
| SCHEMBL2140426 | 0.77 | CHRM2 (0.76) | CHRM2CHRM3 | |
| SCHEMBL1246041 | 0.77 | CHRM3 (0.72) | CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242759-B1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2012-09-12 | — | — | EP | disclosed |