Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 14/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10242031 | 0.93 | ADRB2 (0.44) | ADRB2ADRB1ADRB3CHRM3DRD2 | |
| SCHEMBL10241987 | 0.85 | CHRM3 (0.47) | ADRB2ADRB1CHRM3DRD2 | |
| SCHEMBL10241663 | 0.81 | CHRM3 (0.58) | ADRB2ADRB1CHRM3DRD2 | |
| SCHEMBL12101081 | 0.81 | ADRB2 (0.48) | ADRB2ADRB1ADRB3CHRM3 | |
| SCHEMBL12101020 | 0.80 | CHRM3 (0.44) | ADRB2ADRB1CHRM3 | |
| SCHEMBL10241866 | 0.78 | ADRB2 (0.65) | ADRB2ADRB1CHRM3DRD2DRD3 | |
| SCHEMBL10242798 | 0.78 | CHRM3 (0.59) | ADRB2ADRB1ADRB3CHRM3 | |
| SCHEMBL2143093 | 0.78 | CHRM3 (0.38) | ADRB2CHRM3 | |
| SCHEMBL10242309 | 0.77 | CHRM3 (0.57) | ADRB2ADRB1CHRM3 | |
| SCHEMBL10242006 | 0.77 | CHRM3 (0.54) | ADRB2ADRB1ADRB3CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242759-B1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2012-09-12 | — | — | EP | disclosed |