Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 15/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.36 |
| ▸ | DRD2 | P14416 | 7/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10242295 | 0.89 | ADRB2 (0.63) | ADRB2CHRM3ADRB1DRD2ADRA1D | |
| SCHEMBL10242218 | 0.79 | ADRB2 (0.67) | ADRB2CHRM3ADRB1DRD2ADRA1D | |
| SCHEMBL10242212 | 0.78 | ADRB2 (0.67) | ADRB2CHRM3ADRB1DRD2ADRA1D | |
| SCHEMBL2141561 | 0.77 | CHRM2 (0.46) | CHRM3DRD2CHRM2 | |
| SCHEMBL10242193 | 0.77 | ADRB2 (0.59) | ADRB2CHRM3ADRB1DRD2ADRA1D | |
| SCHEMBL2140442 | 0.77 | ADRB2 (0.56) | ADRB2CHRM3ADRB1DRD2ADRA1D | |
| SCHEMBL2140430 | 0.77 | ADRB2 (0.56) | ADRB2CHRM3ADRB1DRD2ADRA1D | |
| SCHEMBL10242319 | 0.76 | ADRB2 (0.64) | ADRB2CHRM3ADRB1DRD2ADRA1D | |
| SCHEMBL12095843 | 0.76 | ADRB2 (0.61) | ADRB2CHRM3ADRB1DRD2ADRA1D | |
| SCHEMBL10242196 | 0.76 | ADRB2 (0.64) | ADRB2CHRM3ADRB1DRD2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242759-B1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2012-09-12 | — | — | EP | disclosed |