Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 12/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10242438 | 0.94 | CHRM3 (0.47) | ADRB2ADRB1ADRB3CHRM3CHRM2 | |
| SCHEMBL10242436 | 0.91 | CHRM3 (0.47) | ADRB2ADRB1ADRB3CHRM3CHRM2 | |
| SCHEMBL10242460 | 0.84 | CHRM3 (0.58) | ADRB2ADRB1CHRM3CHRM2ADRA1D | |
| SCHEMBL10241547 | 0.84 | ADRB2 (0.50) | ADRB2ADRB1CHRM3CHRM2ADRA1D | |
| SCHEMBL2141525 | 0.83 | CHRM3 (0.44) | ADRB2CHRM3CHRM2 | |
| SCHEMBL2141507 | 0.83 | CHRM3 (0.44) | ADRB2CHRM3CHRM2 | |
| SCHEMBL10242478 | 0.82 | CHRM3 (0.43) | ADRB2ADRB1ADRB3CHRM3CHRM2 | |
| SCHEMBL10242497 | 0.79 | CHRM3 (0.46) | ADRB2ADRB1ADRB3CHRM3CHRM2 | |
| SCHEMBL12101037 | 0.79 | CHRM3 (0.46) | ADRB2ADRB1ADRB3CHRM3CHRM2 | |
| SCHEMBL10241667 | 0.79 | ADRB2 (0.55) | ADRB2ADRB1CHRM3CHRM2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242759-B1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2012-09-12 | — | — | EP | disclosed |