Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19861519 | 0.86 | DGKA (0.48) | CYP1A2GAACYP4F2CYP4A11KMT2A | |
| SCHEMBL2139219 | 0.85 | CYP4F2 (0.57) | CYP1A2GAACYP4F2CYP4A11KMT2A | |
| SCHEMBL2141682 | 0.83 | CYP1A2 (0.46) | CYP1A2GAACYP4F2CYP4A11KMT2A | |
| SCHEMBL26711435 | 0.81 | CYP1A2 (0.46) | CYP1A2GAACYP4F2CYP4A11KMT2A | |
| SCHEMBL8233910 | 0.80 | CYP1A2 (0.57) | CYP1A2GAACYP4F2CYP4A11KMT2A | |
| SCHEMBL25823863 | 0.80 | CYP1A2 (0.57) | CYP1A2GAACYP4F2CYP4A11KMT2A | |
| SCHEMBL12824155 | 0.80 | CYP1A2 (0.57) | CYP1A2GAACYP4F2CYP4A11KMT2A | |
| SCHEMBL19861446 | 0.79 | DGKA (0.53) | CYP1A2GAACYP4F2CYP4A11KMT2A | |
| SCHEMBL26711439 | 0.79 | CYP1A2 (0.48) | CYP1A2GAACYP4F2CYP4A11KMT2A | |
| SCHEMBL21015257 | 0.79 | CYP1A2 (0.52) | CYP1A2GAACYP4F2CYP4A11KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242759-B1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2012-09-12 | — | — | EP | disclosed |