Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLLT1 | Q03111 | 1/20 | 0.56 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | FLT3 | P36888 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | PYGL | P06737 | 1/20 | 0.49 |
| ▸ | PYGM | P11217 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12101148 | 0.88 | MLLT1 (0.58) | MLLT1SMYD3TP53POLBPIN1 | |
| SCHEMBL11888208 | 0.87 | MLLT1 (0.72) | MLLT1SMYD3TP53POLBPIN1 | |
| SCHEMBL11888306 | 0.87 | MLLT1 (0.53) | MLLT1SMYD3TP53POLBPIN1 | |
| SCHEMBL17209759 | 0.86 | MLLT1 (0.70) | MLLT1SMYD3TP53POLBPIN1 | |
| SCHEMBL11888227 | 0.86 | MLLT1 (0.70) | MLLT1SMYD3TP53POLBPIN1 | |
| SCHEMBL17209760 | 0.86 | MLLT1 (0.70) | MLLT1SMYD3TP53POLBPIN1 | |
| SCHEMBL12101155 | 0.85 | SMYD3 (0.76) | MLLT1SMYD3RAB9ANPC1PYGL | |
| SCHEMBL14224769 | 0.81 | MLLT1 (0.52) | MLLT1SMYD3TP53POLBPIN1 | |
| SCHEMBL12101141 | 0.81 | TP53 (0.52) | MLLT1SMYD3TP53POLBPIN1 | |
| SCHEMBL3605634 | 0.81 | GHSR (0.55) | MLLT1SMYD3TP53POLBPIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1577301-B1 | Antithrombotic diaminocyclohexane derivatives | DAIICHI SANKYO CO LTD (JP) | 2012-09-12 | — | — | EP | disclosed |
| EP-2343290-A1 | Diamine derivatives as factor X inhibitors | Daiichi Sankyo Company, Limited (JP) | 2011-07-13 | — | — | EP | disclosed |