Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.40 |
| ▸ | BPTF | Q12830 | 2/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | CLK3 | P49761 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12101301 | 1.00 | F10 (0.53) | F10KLKB1SLC2A1BPTFCLK2 | |
| SCHEMBL12101325 | 0.89 | F10 (0.51) | F10KLKB1SLC2A1BPTFCFD | |
| SCHEMBL12101320 | 0.86 | F10 (0.54) | F10KLKB1CLK2CLK3DYRK1A | |
| SCHEMBL12101303 | 0.82 | F10 (0.52) | F10KLKB1CFD | |
| SCHEMBL13104190 | 0.82 | F10 (0.52) | F10KLKB1CFD | |
| SCHEMBL12101415 | 0.81 | F10 (0.52) | F10KLKB1CFD | |
| SCHEMBL12101343 | 0.81 | F10 (0.54) | F10KLKB1CFD | |
| SCHEMBL13104189 | 0.81 | F10 (0.54) | F10KLKB1CFD | |
| SCHEMBL14434252 | 0.80 | F10 (0.56) | F10KLKB1SLC2A1CFD | |
| SCHEMBL14434674 | 0.80 | F10 (0.53) | F10KLKB1SLC2A1CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051975-B1 | SUBSTITUTED PROLINAMIDES, PRODUCTION THEREOF AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM INT (DE) | 2012-09-12 | — | — | EP | disclosed |