Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CFD | P00746 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8222144 | 1.00 | F10 (0.52) | F10KLKB1KMT2ACFDPOLB | |
| SCHEMBL8227386 | 1.00 | F10 (0.52) | F10KLKB1KMT2ACFDPOLB | |
| SCHEMBL12101360 | 0.93 | F10 (0.52) | F10KLKB1KMT2ACFDPOLB | |
| SCHEMBL8225736 | 0.91 | F10 (0.43) | F10KLKB1KMT2ACFDPOLB | |
| SCHEMBL12101342 | 0.91 | F10 (0.43) | F10KLKB1KMT2ACFDPOLB | |
| SCHEMBL12101341 | 0.91 | F10 (0.43) | F10KLKB1KMT2ACFDPOLB | |
| SCHEMBL13104189 | 0.90 | F10 (0.54) | F10KLKB1CFDTSHRDRD1 | |
| SCHEMBL12371436 | 0.89 | F10 (0.49) | F10KLKB1KMT2ACFDPOLB | |
| SCHEMBL12371437 | 0.89 | F10 (0.49) | F10KLKB1KMT2ACFDPOLB | |
| SCHEMBL8471226 | 0.87 | F10 (0.54) | F10KLKB1KMT2ACFDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051975-B1 | SUBSTITUTED PROLINAMIDES, PRODUCTION THEREOF AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM INT (DE) | 2012-09-12 | — | — | EP | disclosed |