Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CFD | P00746 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8222144 | 0.91 | F10 (0.52) | F10KMT2ACFDNPC1POLB | |
| SCHEMBL12101342 | 0.91 | F10 (0.43) | F10KMT2ACFDNPC1POLB | |
| SCHEMBL8225736 | 0.91 | F10 (0.43) | F10KMT2ACFDNPC1POLB | |
| SCHEMBL12101340 | 0.91 | F10 (0.52) | F10KMT2ACFDNPC1POLB | |
| SCHEMBL8227386 | 0.91 | F10 (0.52) | F10KMT2ACFDNPC1POLB | |
| SCHEMBL14434669 | 0.89 | F10 (0.41) | F10KMT2ACFDNPC1POLB | |
| SCHEMBL15436156 | 0.88 | F10 (0.43) | F10KMT2ACFDNPC1POLB | |
| SCHEMBL14434247 | 0.88 | F10 (0.43) | F10KMT2ACFDNPC1POLB | |
| SCHEMBL14434254 | 0.87 | F10 (0.42) | F10KMT2ACFDNPC1POLB | |
| SCHEMBL12101413 | 0.85 | F10 (0.43) | F10CFDNPC1KLKB1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051975-B1 | SUBSTITUTED PROLINAMIDES, PRODUCTION THEREOF AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM INT (DE) | 2012-09-12 | — | — | EP | disclosed |