Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464556 | 0.72 | CNR2 (0.43) | MAPK14MAPK13MAPTMAPK11MAPK12 | |
| SCHEMBL1463606 | 0.70 | CNR2 (0.74) | MAPK14MAPK13MAPTMAPK11MAPK12 | |
| SCHEMBL66874 | 0.65 | MAPK14 (1.00) | MAPK14MAPK13MAPTMAPK11MAPK12 | |
| SCHEMBL1699062 | 0.62 | MAPK14 (0.61) | MAPK14MAPK13MAPTMAPK11MAPK12 | |
| SCHEMBL469410 | 0.62 | CNR2 (1.00) | MAPK14MAPK13MAPTMAPK11MAPK12 | |
| SCHEMBL12682612 | 0.61 | MAPT (1.00) | MAPK14MAPK13MAPTMAPK11MAPK12 | |
| SCHEMBL7112019 | 0.61 | MAPK14 (0.63) | MAPK14MAPK13MAPTMAPK11MAPK12 | |
| SCHEMBL4139014 | 0.61 | CNR2 (0.56) | MAPK14MAPK13MAPTMAPK11MAPK12 | |
| SCHEMBL13234488 | 0.61 | KDM4E (0.71) | MAPK14MAPK13MAPTMAPK11MAPK12 | |
| SCHEMBL13235035 | 0.61 | MAPK14 (0.76) | MAPK14MAPK13MAPTMAPK11MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-B1 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2012-09-12 | — | — | EP | disclosed |