SCHEMBL12106955

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12106930	0.86	MAPT (0.52)	MAPTCYP2C19POLBABL1RIN1
	SCHEMBL12106938	0.82	MAPT (0.46)	MAPTCYP2C19POLBABL1RIN1
	SCHEMBL1294582	0.80	GAA (0.46)	MAPTPOLBABL1RIN1TDP1
	SCHEMBL12105495	0.79	KDM4E (0.44)	MAPTCYP2C19POLBABL1RIN1
	SCHEMBL12110148	0.78	CYP2C19 (0.61)	MAPTCYP2C19POLBABL1RIN1
	SCHEMBL12106007	0.78	MAPT (0.43)	MAPTCYP2C19POLBABL1RIN1
	SCHEMBL12106939	0.77	MAPT (0.46)	MAPTCYP2C19POLBABL1RIN1
	SCHEMBL14553895	0.77	MAPT (0.42)	MAPTCYP2C19POLBABL1RIN1
	SCHEMBL433839	0.76	CA1 (0.45)	MAPTCYP2C19POLBALDH1A1KDM4E
	SCHEMBL29575116	0.76	CA1 (0.45)	MAPTCYP2C19POLBALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.