Glycine

Glycine

SCHEMBL121072

NCC(=O)[O-].NCC(=O)[O-].[Zn+2]

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D

The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA4 P22748 5/20 0.47
GLRA1 P23415 1/20 0.47
SLC6A9 P48067 1/20 0.47
OR51E2 Q9H255 1/20 0.47
CASP1 P29466 1/20 0.41
FFAR3 O14843 2/20 0.37
HDAC3 O15379 2/20 0.37
HDAC1 Q13547 2/20 0.37
HDAC2 Q92769 2/20 0.37
HDAC8 Q9BY41 2/20 0.37
MEN1 O00255 1/20 0.35
LDHA P00338 1/20 0.35
BLM P54132 1/20 0.35
KMT2A Q03164 1/20 0.35
CA1 P00915 2/20 0.33
GABRR1 P24046 1/20 0.33
CA2 P00918 1/20 0.33
FAHD1 Q6P587 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycine SCHEMBL31626793 1.00 CA4 (0.47) CA4GLRA1SLC6A9OR51E2CASP1
Glycine SCHEMBL28717479 0.96 CA4 (0.44) CA4GLRA1SLC6A9OR51E2CASP1
Glycine SCHEMBL1483142 0.96 CA4 (0.44) CA4GLRA1SLC6A9OR51E2CASP1
Glycine SCHEMBL6865468 0.96 CA4 (0.44) CA4GLRA1SLC6A9OR51E2CASP1
Glycine SCHEMBL9639044 0.96 CA4 (0.44) CA4GLRA1SLC6A9OR51E2CASP1
Glycine SCHEMBL29237170 0.96 CA4 (0.44) CA4GLRA1SLC6A9OR51E2CASP1
Glycine SCHEMBL20239648 0.96 CA4 (0.44) CA4GLRA1SLC6A9OR51E2CASP1
Glycine SCHEMBL3216076 0.96 CA4 (0.44) CA4GLRA1SLC6A9OR51E2CASP1
Glycine SCHEMBL8998221 0.96 CA4 (0.44) CA4GLRA1SLC6A9OR51E2CASP1
Glycine SCHEMBL1085315 0.96 CA4 (0.44) CA4GLRA1SLC6A9OR51E2CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6428 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-224270480-U Amino acid chelated calcium production waste liquid recovery device Shanghai Jiaxiang Industry Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122075533-A S-equol composition for delaying ovarian aging and application thereof 2026-05-26 CN claimed
CN-122056386-A Moisture absorption resistant slow release microcapsule powder and preparation method and application thereof 大连医诺生物股份有限公司 2026-05-19 CN claimed
WO-2026099457-A1 USE OF OXALIC ACID COMPOSITIONS IN DENTAL CARE KING'S COLLEGE LONDON (GB) 2026-05-15 WO claimed
CN-122030612-A Shear-resistant slow-release microcapsule powder and preparation method and application thereof 大连医诺生物股份有限公司 2026-05-15 CN claimed
CN-122004460-A Anti-hypoxia composition containing saussurea involucrata culture and preparation method thereof 山西康宝生物科技有限公司 2026-05-12 CN claimed
CN-122004304-A Low-fat high-nutrition sesame milk and preparation method thereof 河南省农业科学院农产品加工研究中心 2026-05-12 CN claimed
EP-4734970-A1 COMPOSITION COMPRISING HINOKITIOL AND ZINC SALT FOR USE IN THE TREATMENT OF HERPES LABIALIS AAA Investments B.V. (NL) 2026-05-06 EP claimed
EP-3612542-B1 ENERGY-EFFICIENT SOLVENT-FREE METHOD FOR PRODUCING METAL CHELATES TECHNISCHE UNIV CLAUSTHAL (DE) 2026-04-22 EP claimed
EP-3773453-B1 ORAL CARE COMPOSITIONS FOR PROMOTING GUM HEALTH PROCTER & GAMBLE (US) 2026-04-01 EP claimed
US-4647452-A Oral compositions of salicylamides and zinc salts for the synergistic inhibition of dental plaque LEVER BROTHERS COMPANY (US) 1987-03-03 US claimed
EP-0183840-A1 IMPROVEMENT IN THE FLAVOR OF ZINC SUPPLEMENTS FOR ORAL USE. GODFREY SCIENCE & DESIGN INC (US) 1986-06-11 EP claimed
US-4565693-A Deodorant composition COLGATE-PALMOLIVE COMPANY (US) 1986-01-21 US claimed
WO-1986000004-A1 IMPROVEMENT IN THE FLAVOR OF ZINC SUPPLEMENTS FOR ORAL USE GODFREY SCIENCE & DESIGN, INC. (US) 1986-01-03 WO claimed
EP-0131579-A1 PURIFICATION OF ANTIHEMOPHILIA FACTOR VIII BY PRECIPITATION WITH ZINC IONS UNIVERSITY PATENTS, INC. (US) 1985-01-23 EP claimed
WO-1984002651-A1 PURIFICATION OF ANTIHEMOPHILIA FACTOR VIII BY PRECIPITATION WITH ZINC IONS UNIVERSITY PATENTS INC (US) 1984-07-19 WO claimed
US-4425325-A ZINC COMPOUND, GLYCINE LEVER BROTHERS COMPANY (US) 1984-01-10 US claimed
US-4416867-A ZINC SALT, GLYCINE LEVER BROTHERS COMPANY (US) 1983-11-22 US claimed
US-4406886-A FIBRINOGEN REMOVAL UNIVERSITY PATENTS, INC. (US) 1983-09-27 US claimed
US-4339432-A Oral mouthwash containing zinc and glycine LEVER BROTHERS COMPANY (US) 1982-07-13 US claimed