Glycine

Glycine

SCHEMBL6865468

NCC(=O)[O-].NCC(=O)[O-].[N].[Zn+2]

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D

The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA4 P22748 5/20 0.44
GLRA1 P23415 1/20 0.44
SLC6A9 P48067 1/20 0.44
OR51E2 Q9H255 1/20 0.44
CASP1 P29466 1/20 0.39
FFAR3 O14843 2/20 0.35
HDAC3 O15379 2/20 0.35
HDAC1 Q13547 2/20 0.35
HDAC2 Q92769 2/20 0.35
HDAC8 Q9BY41 2/20 0.35
MEN1 O00255 1/20 0.33
LDHA P00338 1/20 0.33
BLM P54132 1/20 0.33
KMT2A Q03164 1/20 0.33
GABRR1 P24046 1/20 0.32
CA2 P00918 1/20 0.32
CA1 P00915 2/20 0.31
FAHD1 Q6P587 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycine SCHEMBL121072 0.96 CA4 (0.47) CA4GLRA1SLC6A9OR51E2CASP1
Glycine SCHEMBL31626793 0.96 CA4 (0.47) CA4GLRA1SLC6A9OR51E2CASP1
Glycine SCHEMBL28717479 0.92 CA4 (0.44) CA4GLRA1SLC6A9OR51E2CASP1
Glycine SCHEMBL3216076 0.92 CA4 (0.44) CA4GLRA1SLC6A9OR51E2CASP1
Glycine SCHEMBL1483142 0.92 CA4 (0.44) CA4GLRA1SLC6A9OR51E2CASP1
Glycine SCHEMBL29237170 0.92 CA4 (0.44) CA4GLRA1SLC6A9OR51E2CASP1
Glycine SCHEMBL8998221 0.92 CA4 (0.44) CA4GLRA1SLC6A9OR51E2CASP1
Glycine SCHEMBL20239648 0.92 CA4 (0.44) CA4GLRA1SLC6A9OR51E2CASP1
Glycine SCHEMBL9639044 0.92 CA4 (0.44) CA4GLRA1SLC6A9OR51E2CASP1
Glycine SCHEMBL3225174 0.92 CA4 (0.44) CA4GLRA1SLC6A9OR51E2CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2652800-B1 RESTRIPPABLE PHOTOVOLTAIC COATINGS ROHM & HAAS (US) 2015-07-22 EP disclosed
EP-2652800-A1 RESTRIPPABLE PHOTOVOLTAIC COATINGS Rohm and Haas Company (US) 2013-10-23 EP disclosed
US-20130247985-A1 RESTRIPPABLE PHOTOVOLTAIC COATINGS ROHM AND HAAS COMPANY (US) 2013-09-26 US disclosed
WO-2012082622-A1 RESTRIPPABLE PHOTOVOLTAIC COATINGS ROHM AND HAAS COMPANY (US) 2012-06-21 WO disclosed
US-6822030-B2 MIXING LIQUID AGGLOMERANTS WITH NONAQUEOUS OR SOLVENT-FREE BLENDS OF ACRYLIC POLYMERS AND POLYURETHANES, THEN APPLYING TO SUBSTRATE SURFACES TO FORM THIN FILMS HAVING UNIFORMITY AND HIGH GLOSS; FLOOR FINISHES ECOLAB INC. 2004-11-23 US disclosed
US-20030204003-A1 Polymer surface coating made by coalescing a polymer particulate with a coalescing agent OLSON KEITH E (US) 2003-10-30 US disclosed
US-6361826-B2 PARTICULARLY USEFUL FOR FINISHING FLOORS ECOLAB INC. 2002-03-26 US disclosed
US-20010043987-A1 Polymer surface coating made by coalescing a polymer particulate with a coalescing agent ECOLAB INC. 2001-11-22 US disclosed
WO-2000064597-A1 POLYMER SURFACE COATING MADE BY COALESCING POLYMER PARTICULATE WITH A COALESCING AGENT ECOLAB INC. (US) 2000-11-02 WO disclosed
US-4168255-A Oligomeric aqueous finishes ROHM AND HAAS COMPANY (US) 1979-09-18 US disclosed
US-4145465-A CROSSLINKED ADDITION POLYMER ROHM AND HAAS COMPANY (US) 1979-03-20 US disclosed
US-4017662-A LOW MOLECULAR WEIGHT HYDROPHILIC ADDITION COPOLYMER ROHM AND HAAS COMPANY (US) 1977-04-12 US disclosed