Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122466 | 0.91 | ELANE (0.77) | ELANECYP2C9CYP2C19 | |
| SCHEMBL123573 | 0.90 | ELANE (0.65) | ELANECYP2C9CYP2C19 | |
| SCHEMBL121886 | 0.89 | ELANE (0.64) | ELANECYP2C9CYP2C19 | |
| SCHEMBL121094 | 0.89 | ELANE (0.72) | ELANECYP2C9CYP2C19 | |
| SCHEMBL123276 | 0.89 | ELANE (0.58) | ELANECYP2C9CYP2C19 | |
| SCHEMBL120539 | 0.89 | ELANE (0.73) | ELANECYP2C9CYP2C19 | |
| SCHEMBL123028 | 0.87 | ELANE (0.71) | ELANECYP2C9CYP2C19 | |
| SCHEMBL123135 | 0.86 | ELANE (0.82) | ELANECYP2C9CYP2C19 | |
| SCHEMBL172162 | 0.86 | ELANE (0.82) | ELANECYP2C9CYP2C19 | |
| SCHEMBL126645 | 0.84 | ELANE (0.64) | ELANECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234985-B1 | 4-(4-CYANO-2-THIOARYL)DIHYDROPYRIMIDINONES AND USE THEREOF | Bayer Pharma AG (DE) | 2012-03-07 | — | — | EP | disclosed |