SCHEMBL12112338

SCHEMBL12112338

CCC(C)C(=O)OCCOCCOc1ccc2cc(C#N)ccc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.44
▸ ALDH1A1 P00352 1/20 0.44
▸ KDM4E B2RXH2 2/20 0.40
▸ TDP1 Q9NUW8 2/20 0.40
▸ MAPK1 P28482 1/20 0.40
▸ SLC6A2 P23975 4/20 0.40
▸ SLC6A4 P31645 4/20 0.40
▸ SLC6A3 Q01959 2/20 0.40
▸ PPARG P37231 2/20 0.40
▸ PPARD Q03181 2/20 0.40
▸ PPARA Q07869 2/20 0.40
▸ HRH3 Q9Y5N1 2/20 0.39
▸ MMP2 P08253 3/20 0.39
▸ MMP3 P08254 2/20 0.39
▸ HTR3A P46098 1/20 0.39
▸ KCNH2 Q12809 1/20 0.39
▸ ALK Q9UM73 1/20 0.38
▸ ACACB O00763 1/20 0.37
▸ SCN9A Q15858 2/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26812832 1.00 MAPT (0.44) MAPTALDH1A1KDM4ETDP1MAPK1
SCHEMBL12347962 0.90 ALDH1A1 (0.54) MAPTALDH1A1KDM4EHRH3MMP2
SCHEMBL12347968 0.86 ALDH1A1 (0.57) MAPTALDH1A1PPARDPPARAHRH3
SCHEMBL25123495 0.85 MAPT (0.48) MAPTALDH1A1KDM4ETDP1MAPK1
SCHEMBL12112350 0.85 PLAU (0.40) MAPTALDH1A1KDM4ETDP1HRH3
SCHEMBL26812863 0.84 SCN9A (0.45) MAPTALDH1A1KDM4ETDP1MAPK1
SCHEMBL21938931 0.84 MAPT (0.52) MAPTALDH1A1KDM4ETDP1MAPK1
SCHEMBL22924872 0.84 MAPT (0.52) MAPTALDH1A1KDM4ETDP1MAPK1
SCHEMBL26812815 0.84 KDM4E (0.60) MAPTALDH1A1KDM4ETDP1MAPK1
SCHEMBL9880796 0.84 KDM4E (0.60) MAPTALDH1A1KDM4ETDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240069257-A1 CHOLESTERIC LIQUID CRYSTAL LAYER, METHOD OF FORMING CHOLESTERIC LIQUID CRYSTAL LAYER, LAMINATE, LIGHT GUIDE ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2024-02-29 — — US disclosed
US-11828960-B2 Cholesteric liquid crystal layer, method of forming cholesteric liquid crystal layer, laminate, light guide element, and image display device FUJIFILM CORPORATION (JP) 2023-11-28 — — US disclosed
US-8053040-B2 Liquid crystal composition, retardation plate, liquid crystal display device, and process for producing retardation plate FUJIFILM CORPORATION (JP) 2011-11-08 — — US disclosed
US-20100078592-A1 LIQUID CRYSTAL COMPOSITION, RETARDATION PLATE, LIQUID CRYSTAL DISPLAY DEVICE, AND PROCESS FOR PRODUCING RETARDATION PLATE FUJIFILM CORPORATION (JP) 2010-04-01 — — US disclosed
Send feedback